نتایج جستجو برای: haart

تعداد نتایج: 4613  

Journal: :PLoS Pathogens 2007
Ahmad R Sedaghat Janet D Siliciano Timothy P Brennan Claus O Wilke Robert F Siliciano

Whereas cells productively infected with human immunodeficiency virus type 1 (HIV-1) decay rapidly in the setting of highly active antiretroviral therapy (HAART), latently infected resting CD4(+) T cells decay very slowly, persisting for the lifetime of the patient and thus forming a stable reservoir for HIV-1. It has been suggested that the stability of the latent reservoir is due to low-level...

Journal: :The Journal of clinical investigation 1999
G M Ortiz D F Nixon A Trkola J Binley X Jin S Bonhoeffer P J Kuebler S M Donahoe M A Demoitie W M Kakimoto T Ketas B Clas J J Heymann L Zhang Y Cao A Hurley J P Moore D D Ho M Markowitz

Therapeutic intervention with highly active antiretroviral therapy (HAART) can lead to suppression of HIV-1 plasma viremia to undetectable levels for 3 or more years. However, adherence to complex drug regimens can prove problematic, and subjects may temporarily discontinue HAART for variable periods. We studied 6 HIV-1-infected individuals who stopped therapy. Off HAART, levels of viremia were...

2010
Kim C Mansky

Highly active antiretroviral therapy (HAART) has had a profound impact on improving the long-term prognosis for individuals infected with human immunodeficiency virus (HIV). HAART has been available for close to two decades, and now a significant number of patients with access to HAART are over the age of 50 years. Many clinical studies have indicated that HIV infection, as well as components o...

Journal: :Salud publica de Mexico 2008
Sergio Bautista-Arredondo Tania Dmytraczenko Gilbert Kombe Stefano M Bertozzi

OBJECTIVE To determine the net effect of introducing highly active antiretroviral treatment (HAART) in Mexico on total annual per-patient costs for HIV/AIDS care, taking into account potential savings from treatment of opportunistic infections and hospitalizations. MATERIAL AND METHODS A multi-center, retrospective patient chart review and collection of unit cost data were performed to descri...

2016
Brenda Crabtree-Ramírez Yanink Caro-Vega Bryan E. Shepherd Beatriz Grinsztejn Marcelo Wolff Claudia P. Cortes Denis Padgett Gabriela Carriquiry Valeria Fink Karu Jayathilake Anna K. Person Catherine McGowan Juan Sierra-Madero

BACKGROUND Since 2009, earlier initiation of highly active antiretroviral therapy (HAART) after an opportunistic infection (OI) has been recommended based on lower risks of death and AIDS-related progression found in clinical trials. Delay in HAART initiation after OIs may be an important barrier for successful outcomes in patients with advanced disease. Timing of HAART initiation after an OI i...

2010
Sadeep Shrestha Staci L Sudenga Jennifer S Smith Laura H Bachmann Craig M Wilson Mirjam C Kempf

BACKGROUND The implementation of highly active antiretroviral therapy (HAART) among HIV-positive patients results in immune reconstitution, slower progression of HIV disease, and a decrease in the occurrence of opportunistic infections. However, the impact of HAART on cervical human papillomavirus (HPV) infection, clearance, and persistence in high-risk adolescents remains controversial. METH...

2005
Tsitsi Mildred Magure

Objectives: to review studies on the effect of antiretroviral therapy on the short term incidence, prevalence, regression, recurrence and the progression rates of pre-malignant conditions of the cervix in women infected with HIV. Outcome measures: the effect of HAART therapy on the incidence, prevalence, regression, progression and recurrence rates of cervical intraepithelial neoclassic. Inclus...

2011
Julius Atashili Jennifer S. Smith Adaora A. Adimora Joseph Eron William C. Miller Evan Myers

BACKGROUND Despite having high cervical cancer incidence and mortality rates, screening for cervical precancerous lesions remains infrequent in sub-Saharan Africa. The need to screen HIV-positive women because of the higher prevalence and faster progression of cervical precancerous lesions may be heightened by the increased access to highly-active antiretroviral therapy (HAART). Policymakers ne...

Journal: :Antiviral therapy 2010
Todd T Brown Susheel P Patil Lisa P Jacobson Joseph B Margolick Alison M Laffan Rebecca J Godfrey Jacquett R Johnson Lisette M Johnson-Hill Sandra M Reynolds Alan R Schwartz Philip L Smith

BACKGROUND Body mass index (BMI), waist circumference (WC) and neck circumference (NC) are important screening tools for sleep disordered breathing (SDB); however, the utility of anthropometry for this purpose has not been evaluated among HIV-positive patients. METHODS HIV-negative men (n=60), HIV-positive men receiving highly active antiretroviral therapy (HIV-positive/HAART; n=58) and HIV-p...

Journal: :AIDS research and human retroviruses 2006
M Angeles Rodríguez-Arenas Inmaculada Jarrín Julia del Amo José A Iribarren Santiago Moreno Pompeyo Viciana Alejandro Peña José L Gómez Sirvent Francesc Vidal José Lacruz Félix Gutierrez José A Oteo Román Asencio Jesús Castilla Santiago Perez Hoyos

Differences in the uptake and time to initiation of highly active antiretroviral therapy (HAART), the virological response to HAART, and survival from AIDS by transmission category were analyzed. A multicenter hospital-based cohort of HIV-infected patients attending 10 hospitals in Spain from January 1997 to December 2003 was used. Cross-checks with the National AIDS Registry were performed. Co...

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