The cyclic-imide-hydrolyzing activity of a prokaryotic cyclic-ureide-hydrolyzing enzyme, D-hydantoinase, was investigated. The enzyme hydrolyzed cyclic imides with bulky substituents such as 2-methylsuccinimide, 2-phenylsuccinimide, phthalimide, and 3,4-pyridine dicarboximide to the corresponding half-amides. However, simple cyclic imides without substituents, which are substrates of imidase (i...

To compare the effectiveness of full- and partial-mouth disinfection for halitosis control, patients were assigned to treatment with full-mouth therapy (complete scaling and root planing in one stage within 24 h) or conventional therapy in quadrants (scaling and root planing performed by quadrant over a period of 4 weeks) (n = 90 for each group). Both groups were then subdivided: half the patie...

PEGylation is a well-established technique utilized to overcome the problems related to the therapeutic applications of peptides and proteins. Reasons for the PEGylation of these biological macromolecules include reducing immunogenicity, proteolytic degradation and rapid clearance from blood circulation. Octreotide is an octapeptide analogue of naturally-occurred somatostatin. This peptide has ...

PEGylation is a well-established technique utilized to overcome the problems related to the therapeutic applications of peptides and proteins. Reasons for the PEGylation of these biological macromolecules include reducing immunogenicity, proteolytic degradation and rapid clearance from blood circulation. Octreotide is an octapeptide analogue of naturally-occurred somatostatin. This peptide has ...

The plane strain deformation of an isotropic, homogeneous, poroelastic medium caused by an inclined line-load is studied using the Biot linearized theory for fluid saturated porous materials. The analytical expressions for the displacements and stresses in the medium are obtained by applying suitable boundary conditions. The solutions are obtained analytically for the limiting case of undrained...

Sulfur mustard is one of the major potent chemical warfare agents. It was widely used against not only military personnel but also civilian people ofIranduring the last years (1984–1988) of the Iraq–Iran war. A number of studies were performed regarding the acute and long-term consequences of sulfur mustard on respiratory system. Currently, many aspects of leading respiratory disorder that was ...

Software often goes through a variety of extensions during its lifetime: adding new fields or new variants to a data structure, retroactively creating new type abstractions, and adding new operations on a data structure. As characterized by the extensibility problem, it should be possible to apply any combination of these types of extensions in any order. Mainstream object-oriented languages, h...

A 14-month-old child was diagnosed with a Veau Class II cleft palate. Von Langenbeck palatoplasty was performed for the right palate, and V-Y pushback palatoplasty was performed for the left palate. The child did not have a special problem during the surgery, and the authors were able to elongate the cleft by 10 mm. Contrary to preoperative concerns regarding the hybrid use of palatoplasties, t...

Example An operating system is a widely-used example of a complex concurrent system that manages many different types of applications and hardware. For instance, it coordinates and demultiplexes the communication between standard Internet networking applications, such as telnet, ftp, smtp, dns, and inetd, and hardware I/O devices, such as network interfaces, disk controllers, end-user terminals...

The Chlamydomonas reinhardtii transcriptome was characterized from nutrient-replete and sulfur-depleted wild-type and snrk2.1 mutant cells. This mutant is null for the regulatory Ser-Thr kinase SNRK2.1, which is required for acclimation of the alga to sulfur deprivation. The transcriptome analyses used microarray hybridization and RNA-seq technology. Quantitative RT-PCR evaluation of the result...