The diagnosis of cutaneous and subcutaneous spindle cell neoplasms in children is often challenging has potential therapeutic prognostic implications. Although correctly diagnosing dermatofibrosarcoma protuberans infantile fibrosarcoma paramount, pathologists should not ignore a number diagnostic pitfalls linked to mostly rare tumors with completely different clinical outcomes. In the last deca...

etrorectal cystic hamartoma are rare tumors of developmental origin usually diagnosed as an incidental finding in adult patients. We present such a case in a 33-year-old lady who presented with acute retention of urine. Ultrasound abdomen showed a retrorectal cystic mass (15 x 10 cm), which, was confirmed on computerized tomography (CT) scan. Exploratory laparotomy via a lower midline incision ...

HISTOLOGICAL EXAMINATION The round tumour consisted of chondromatous islands separated by loose, partly myxomatous connective tissue with areas containing fat cells, and clefts lined with small cylindrical or cuboid epithelial cells. Cilia were seen in some places on the surface of the epithelial cells. About three-quarters of the tumour consisted of this typical hamartoma-like picture, and the...

Hypothalamic hamartoma is a potentially complex entity with diverse clinical manifestations. We report a case of gelastic seizures associated with a hypothalamic hamartoma, which followed a benign course. A 31-year-old woman with episodes of laughter was referred for diagnostic evaluation. Her initial MRI and EEG were reported as normal. However, her episodes of laughter were typical of gelasti...

The radiologic features of intralobar pulmonary sequestration (ILPS) have been describe and include the identification of a feeding systemic artery with venous drainage through pulmonary veins. Primary sequestration associated with typical hamartoma signs is really rare and has been described only once. We describe a patient with ILPS whose radiographic findings were unusual for two reasons. Fi...

Basaloid follicular hamartoma (BFH) is a rare benign adnexal tumor with variable clinical presentation. We report a case of a 64-year-old man, who presented with an incidental finding of a 3mm hyperpigmented macule on his cheek. Dermoscopy revealed a structureless blue lesion. Histopathology examination showed interconnecting lobules and cords of bland pigmented epithelial cells within the derm...

OBJECTIVE To emphasize the contribution of superparamagnetic iron oxide (SPIO) contrast agent in the diagnosis of the splenic hamartoma. CLINICAL PRESENTATION AND INTERVENTION A 63-year-old female was admitted to our hospital with diffuse abdominal pain. An ultrasound examination revealed a 5 × 4 cm solid lesion in the spleen. Dynamic gadolinium-enhanced magnetic resonance imaging (MRI) of th...

Fibrous hamartoma of infancy is a rare benign tumour with local infiltration. The lesion is usually found in the upper torso and rarely occurs in the genital region. Diagnosis before surgery is rare, and complete excision is essential to prevent recurrence. We present a case in which fibrous hamartoma of infancy involving the spermatic cord was found. A pre-operative clinical diagnosis could no...

Myoepithelial hamartoma is a very rare submucosal tumor of the stomach. Magnus-Alsleben first described 5 cases of this tumor in 1903. More recently (1993) Vandelli et al. published a review of the literature comprising only 33 cases. Histologically, the tumor is characterized by hypertrophic smooth muscle bands surrounding diverse epithelial elements that can be arranged in different ways: as ...

A 10-month-old female, Wire-haired Pointing Griffon dog had a hamartoma of the hypothalamus. Episodes of sudden flaccid collapse had increased in frequency and duration for 7 months. Cerebrospinal fluid pressure was normal. A flat, pedunculated mass, 2.5 X 3.0 X 0.9 cm, covered the brain stem between the pituitary gland and pons. Its 1.2-cm-diameter connection to the hypothalamus obliterated th...