BACKGROUND We have studied the possibility that low-dose treatment utilizing the inhibition that may occur between two drugs at the same site of human serum albumin (HSA) improves the pharmacological effects. The purpose is to elucidate the differences in the binding capacities of sites I and II of HSA between pre-haemodialysis (HD) and post-HD in patients with end-stage renal disease. METHOD...

Hemodialysis (HD) patients are more susceptible to infective endocarditis (IE) due to the increased risk of bacterial invasion through intravascular access. However, it remains unclear whether the causative organisms and outcomes of IE in HD patients differ from those in non-HD patients. This study clarified the differences in clinical presentation and outcomes between HD and non-HD patients. A...

background: oral contraceptive pills effectiveness is lower in actual use than in clinical trials. the views of a group of married iranian women were sought as a step toward improving the enhanced use of contraceptive pills. methods: two focus groups of current pill users (n=13) and two focus groups of women not currently taking the pills (n=14) were held. leaders trained facilitators; themes w...

context the occurrence of intradialytic hypotension (idh) during hemodialysis (hd) continues to be a main problem in patients with esrd (end-stage kidney disease). it also negatively affects health-related quality of life. we aimed to determine vasopressin effect in decreasing idh. evidence acquisition we reviewed clinical and experimental literature in a variety of sources, including pubmed, c...

The morphology of the material surrounding Her-big Ae/Be stars is still a topic of debate. Distinct models with different geometry and optical thickness are found to be compatible with the observed IR excess. This indicates that it is not possible to resolve this question by only looking at the fluxes. Therefore, this paper compares three known Herbig Ae/Be stars with very similar energy distri...

On the basis of Coravel observations, we present orbital parameters for 10 spectroscopic-binary systems including an evolved star, namely HD 13530, HD 28591, HD 47415, HD 78414, HD 123999, HD 153751, HD 174881, HD 179094, HD 212280 and HD 217188. The most significant result is related to HD 13530, for which we have found an orbital period of 1575.48±1.63 days and an eccentricity of 0.8815. Such...

BACKGROUND We designed a study to assess the association of oral contraceptive use and the development of breast cancer for women in the following groups: (1) ever oral contraceptive users, (2) long-term oral contraceptive users, and (3) oral contraceptive users before a first full-term pregnancy. METHODS A MEDLINE search of studies published in English from 1966 to 1990 was conducted using t...