Institute of Nuclear Sciences Applied to Health (ICNAS), University of Coimbra, Portugal In order to ensure the safe usage of new radiopharmaceuticals in Positron Emission Tomography (PET), it is necessary to quantify the doses delivered to the organs and tissues within the patients’ bodies. A framework that allows estimating the dose delivered by PET has been established by the MIRD Committee ...

The number of Positron Emission Tomography (PET) centers has been growing rapidly. Many of the new facilities have been retrofitted into existing imaging centers and hospitals. Space in the facilities is often cramped, resulting in the hot lab, patient quiet rooms, and the scanners frequently being placed in close proximity to uncontrolled areas where non-occupational dose limits apply. Of part...

primary leiomyosarcoma of the heart is extremely rare and found in about 0.2% of all cardiac tumors. here in a 26-year-old man with progressive dyspnea, which had started since 2 months ago, is presented. echocardiography revealed a left atrial mass, which was suggestive for a atrial myxoma.on the surgery, a tumoral tissue in the left atrium and pulmonary veins with attachment to peripheral sof...

a 5-year-old girl was admitted to the hospital with chest pain, fever and dyspnea. physical examination showed normal heart sounds, diminished pulmonary sounds in the left hemithorax and a normal ecg. on chest x-ray the heart was slightly enlarged with moderate left pleural effusion. ct scan revealed pleural effusion and a hypodense mass at the apex of the heart. a cystic mass was detected by e...

background: ischemic heart disease is the leading cause of death in most societies. in a pathophysiologic point of view, it chiefly results from the formation of thrombus in coronary arteries which could not be only prevented by aspirin. many of clinical trials have shown the long-term benefits of antiplatelet drugs in reducing the risk of thrombotic accidents. objectives: clopidogrel is a thie...

background: severe and prolonged physical training is associated with morphological and physiological cardiac changes, often termed as the “athlete’s heart”. echocardiographic features peculiar to elite iranian athletes have not been previously described. the aim was to examine the echocardiographic characteristics of highly trained iranian athletes involved in three different sports.   methods...

Cardiac diseases are common post-stroke and are associated with increased morbidity and mortality. One possible mechanism of acute cardiac injury is the neurogenic myocardial damage, where the cerebral injury is disturbing the normal sympathetic and parasympathetic neuronal outflow to the heart leading to cardiac damage including myocardial infarctions. The exact mechanism is not completely und...

background: this study was undertaken to compare the outcome in patients with moderate to severe ischemic mitral regurgitation (imr) undergoing coronary artery bypass grafting (cabg) with either mitral valve repair or mitral valve replacement. methods: between march 2002 and february 2005, 49 consecutive patients (mean age: 62.84±8.42 years; mean euroscore: 10.03±3.12) with coronary artery dise...

background: pregnant patients with mechanical heart valves require anticoagulation. the risk of bleeding and embryopathy associated with oral anticoagulants must be weighed against the risk of valve thrombosis. methods: in this prospective study, undertaken between 1999 and 2009, 53 pregnancies (47 women with mechanical mitral valves; 29.8 ± 4.8 years old) were studied. patients were divided in...

evaluation of the cardiovascular system of canine pediatrics requires awareness of the anatomical and physiological changes occurring from birth to six months of age. the aim of this study was to report electrocardiographic changes in the littermate mongrel dogs from birth tosix months. serial six-lead electrocardiograms were recorded from ten normal littermate mongrel dogs kept on right latera...