normal 0 false false false microsoftinternetexplorer4 the present study was carried out to determine the effect of hydroalcoholic extract of tylophora indica (heti) on experimentally-induced myocardial infarction (mi) in rats. albino rats were treated with heti at doses of 100 mg/kg, (heti-100) or 200 mg/kg (heti-200) and propranolol 10 mg/kg (pro-10) for 30 days orally. mi was induced by subcu...

Myocardial protection by pre-conditioning involves increasing the tolerance to ischaemia-reperfusion injury and can be achieved by either mechanical or pharmacological means. Pre-conditioning involves the therapeutic manoeuvre being applied before the start of ischaemia while post-conditioning applies the manoeuvre after the start of ischaemia. The initial method for achieving myocardial protec...

A number of type 1 receptor cytokine family members protect the heart from acute and chronic oxidative stress. This protection involves activation of two intracellular signaling cascades: the reperfusion injury salvage kinase (RISK) pathway, which entails activation of phosphatidylinositol 3-kinase (PI3-kinase) and ERK1/2, and JAK-STAT signaling, which involves activation of transcription facto...

-----------------------------------.... Retrograde coronary sinus perfusion may provide equal if not better myocardial protection than antegrade cardioplegia during certain heart surgeries. The coronary venous system can be divided into the greater and lesser systems and veno-venous and arterio-venous anastomoses. Venous drainage varies greatly and retrograde coronary sinus perfusion depends on...

Favourable lifestyles promote cardiovascular protection. Exercise can induce beneficial changes in the genome that decrease low-density lipoprotein cholesterol (LDL-C) and increase anti-inflammatory markers. The Mediterranean dietary pattern, fortified by nuts, while not reducing weight, reduces mortality. Lifestyle changes combined with statin therapy provide potent protection against coronary...