background: heat stress is one of the most important consequences of occupational heat exposure worldwide. current heat stress indexes are not suitable for heat strain screening in developing countries due to their inherent and applied limitations. a new observation and subjective screening method is required that needs no instrument. in this study, a scale is developed based on the most import...

We show that, in dimension higher than one, heat diffusion and viscosity cannot arrest thermal collapse in a freely evolving dilute granular gas, even in the absence of gravity. Thermal collapse involves a finite-time blowup of the gas density. It was predicted earlier in ideal, Euler hydrodynamics of dilute granular gases in the absence of gravity, and in nonideal, Navier-Stokes granular hydro...

A unique property of the photodynamic signal transduction inhibitor hypericin is functionality in the dark. We show in tumor cells that hypericin targets the heat shock protein (Hsp) 90 chaperone but not Hsp70 (Hsc70) to enhanced ubiquitinylation. As a consequence Hsp90 chaperone functionality is abrogated and the client proteins, mutant p53, Cdk4, Raf-1, and Plk, are displaced from complexes w...

The spg1 gene (septum-promoting GTPase) was cloned as a multicopy suppressor of a dominant-negative mutant of the Cdc7p kinase. It encodes a small GTPase of the Ras superfamily. spg1 is an essential gene. Null or heat-sensitive alleles do not make a division septum, but growth, S-phase, and mitosis continue in the absence of cell division, producing elongated, multinucleate cells. Increased exp...

A unique property of the photodynamic signal transduction inhibitor hypericin is functionality in the dark. We show in tumor cells that hypericin targets the heat shock protein (Hsp) 90 chaperone but not Hsp70 (Hsc70) to enhanced ubiquitinylation. As a consequence Hsp90 chaperone functionality is abrogated and the client proteins, mutant p53, Cdk4, Raf-1, and Plk, are displaced from complexes w...

The ability of glycopeptides, isolated from bovine cerebral cortex, to alter cell division was studied by cell-cycle analyses. The results showed that glycopeptides arrested baby hamster kidney (BHK)-21 cells and Chinese hamster ovary (CHO) cells in the G2 phase of the cell cycle. Upon removal of the growth inhibition from arrested BHK-21 cells, the mitotic index in colchicine-treated cultures ...

Many studies are performed by researchers about Shell and Tube Heat Exchanger but the Multi-Objective Big Bang-Big Crunch algorithm (MOBBA) technique has never been used in such studies. This paper presents application of Thermal-Economic Multi-Objective Optimization of Shell and Tube Heat Exchanger Using MOBBA. For optimal design of a shell and tube heat exchanger, it was first thermally model...

in this paper, free convection in an inclined stepped chamber has been studied. one wall of this enclosure is kept cold and the opposite wall equipped with constant heat source. the remaining walls are maintained adiabatic. there is one adiabatic step on the bottom wall. the aim of the present study is to forecast the effect of raleigh number, slope of enclosure, step dimension, and heat source...

heat stress is a major environmental stress limiting wheat productivity in most cereal growing areas of the world. in order to map and characterize quantitative trait loci controlling heat tolerance, 144 recombinant inbred lines deriving from the cross of kauz and mtrwa116 were assessed in a greenhouse and growth chamber at 35°c. one hundred and sixty six ssr and 3 aflp markers were used to...