OBJECTIVE Describe the demographic characteristics and disorders of patients with diagnosis of Macrophage Activation Syndrome (MAS) in the December 2008 - January 2014 period. METHODS Medical records were reviewed from diagnosis of MAS and after discharge until January 2014. Patients were divided into 4 groups according to the primary disease: Autoimmune (AI), Hemato - oncologic (HO), Infecti...

We report the first nosocomial outbreak of human metapneumovirus (hMPV) infection in a pediatric patient population. Among 15 pediatric hMPV infections from March to May 2007, there was a nosocomial outbreak involving two patients sharing a room in a hemato-oncology ward with a patient with a community-acquired case of hMPV infection. The estimated incubation period was 7 to 9 days for a sympto...

The aim of this research is to evaluate a diagnostic model for uncovering an aflatoxicosis outbreak in sheep. The diagnostic model is based on differentiation between an aflatoxicosis suspected herd (ASH) and a control herd (CH) including, clinical findings, feed analysis for aflatoxin and other nutrients, hemato-chemical and biochemical profiles, histopathologic changes, and residual aflatoxin...

response varied significantly with the dose of porphyrin given: tumors of all 27 mice (100%) who received 0.05 mg of "hemato porphyrin" or its copper complex showed grossly complete re gression and did not recur during the following 84-86-day study period, while such regression was seen in only 5 of 126 mice (4%) treated by injection with the other dose levels of porphyrin or with vehicle alone...

The present study was conducted to determine the hematobiochemical analysis of ostrich (Struthio camelus) with respect gender and progressive age. A total 40 apparently healthy ostriches both genders two age groups; young one (1 year 2.4 years: group A); adult (2.5 years 5 B) in equal number were used this study. Blood samples collected from wing vein maintained farms near Gogra Pakistan. For h...

Hematopoietic stem cells (HSCs) are the best characterized adult stem cells and the only stem cell type in routine clinical use. The concept of stem cell transplantation laid the foundations for the development of novel cell therapies within, and even outside, the hematopoietic system. Here, we report on the history of hematopoietic cell transplantation (HCT) and of HSC isolation, we briefly su...

Human endogenous retrovirus (HERVs) integrated in the human genome millions of years ago and became a stable part of the inherited genetic material. Most of these HERVs are dysfunctional due to numerous mutations and thus making it impossible to generate a full, infectious retrovirus particle from a single genetic locus. However, many HERVs are still exceptionally well preserved and maintain Op...

Brain tumors are rare neoplasms, however, they represent the second commonest cancer in childhood (the first being hemato-lymphoid neoplasms) and correspond to the main solid tumor in the pediatric context (ages 0-19 years) [1]. In this setting, gliomas, and particularly astrocytomas are the leading group. Pilocytic astrocytoma (PA) is the commonest brain tumor in the ages 5-14 years and the se...

Bone marrow from old (greater than 2 yr of age) and young (8-10 wk of age) male C3H/HeJ mice was grown in long-term bone marrow cultures and assayed for weekly hematopoietic stem cell (CFUs) production and interval self-renewal capacity (R5). Greater numbers of CFUs were noted in old marrow as compared to young marrow cultures over the first 4 wk duration, but subsequently, greater numbers of C...