نتایج جستجو برای: hemiplegic migraine

تعداد نتایج: 14930  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2017
Stuart M Cain Barry Bohnet Jeffrey LeDue Andrew C Yung Esperanza Garcia John R Tyson Sascha R A Alles Huili Han Arn M J M van den Maagdenberg Piotr Kozlowski Brian A MacVicar Terrance P Snutch

Migraine is characterized by severe headaches that can be preceded by an aura likely caused by cortical spreading depression (SD). The antiepileptic pregabalin (Lyrica) shows clinical promise for migraine therapy, although its efficacy and mechanism of action are unclear. As detected by diffusion-weighted MRI (DW-MRI) in wild-type (WT) mice, the acute systemic administration of pregabalin incre...

Journal: :Molecular bioSystems 2015
Reinald Shyti Isabelle Kohler Bart Schoenmaker Rico J E Derks Michel D Ferrari Else A Tolner Oleg A Mayboroda Arn M J M van den Maagdenberg

Migraine is a common brain disorder characterized by recurrent attacks of severe headaches and other neurological symptoms. In one-third of patients headaches are accompanied by auras, which consist of transient visual and sensory disturbances, believed to be caused by cortical spreading depression (CSD). CSD is characterized by a wave of neuronal and glial depolarization with concomitant chang...

Journal: :Clinical science 2001
P Wilmshurst S Nightingale

A relationship between migraine with aura and the presence of right-to-left shunts has been reported in two studies. Right-to-left shunts are also associated with some forms of decompression illness. While conducting research in divers with decompression illness, it was our impression that divers with a large shunt often had a history of migraine with aura in everyday life and after dives. Ther...

Journal: :PloS one 2015
Maria Isabel Bahamonde Selma Angèlica Serra Oliver Drechsel Rubayte Rahman Anna Marcé-Grau Marta Prieto Stephan Ossowski Alfons Macaya José M Fernández-Fernández

Mutations in the CACNA1A gene, encoding the pore-forming CaV2.1 (P/Q-type) channel α1A subunit, result in heterogeneous human neurological disorders, including familial and sporadic hemiplegic migraine along with episodic and progressive forms of ataxia. Hemiplegic Migraine (HM) mutations induce gain-of-channel function, mainly by shifting channel activation to lower voltages, whereas ataxia mu...

2005
James T. Blodgett John E. Lundquist

JUSTIFICATION: Armillaria root disease is associated with various forest tree declines in the Rocky Mountain Region and has been suggested to play a role in tree mortality that is usually attributed only to bark beetles. Armillaria has been documented as a major forest pest in the states surrounding Wyoming, yet an evaluation of the significance of this root pathogen in Wyoming is lacking. Give...

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