This project focuses on characterizing intravenous (IV) medication administration in an intensive care unit at a partner hospital. Information regarding IV medication dose was extracted from MIMIC II, a large database containing real patient data; this information was used to characterize the use of twelve hemodynamic drugs. Characterization was performed by extracting features such as maximum ...

This project focuses on characterizing intravenous (IV) medication administration in an intensive care unit at a partner hospital. Information regarding IV medication dose was extracted from MIMIC II, a large database containing real patient data; this information was used to characterize the use of twelve hemodynamic drugs. Characterization was performed by extracting features such as maximum ...

Mitochondrial Ca(2+) uptake, central to neural metabolism and function, is diminished in aging whereas enhanced after acute/sub-acute traumatic brain injury. To develop relevant translational models for these neuropathologies, we determined the impact of perturbed mitochondrial Ca(2+) uptake capacities on intrinsic brain activity using clinically relevant markers. From a multi-compartment estim...

•The aim of hemodynamic management is to optimize the amount oxygen delivered tissues.•Because direct monitoring remains difficult, variables are monitored instead.•Hemodynamic itself does not improve patient outcomes and needs be combined with treatment protocols.•Pressures, from arterial blood pressure through pulmonary artery occlusion pressure, can measured using invasive catheters, but sub...

A growing fraction of the clinical duties of Nephrologists is undertaken inside intensive care units. While assessing patients with acute renal failure in the context of circulatory collapse, which are also edematous and/or with impaired gas exchanges, the Nephrologist must decide between two opposing therapies: 1) remove volume with the aid of dialysis or diuretics to improve the edematous sta...

Accumulation of intra-abdominal visceral fat and of adipocyte’s dysfunction are considered the cellular basis of metabolic syndrome (MetS), associated with heightened risk for cardiovascular disease and cardiovascular mortality [1-4]. Population-based studies indicated an association between MetS and abnormal left ventricular (LV) geometry [5,6]. It is well known that several factors, both hemo...

Introduction Coherent spontaneous hemodynamic fluctuations have been widely observed in many brain networks of different species, and they were hypothesized to reflect underlying “functional connectivity” [1] of the brain and imply many “resting networks” . Since it is known that the anesthesia can significantly affect brain activity and state; it can probably also influence these resting netwo...

The purpose of this review is to discuss the management of the low cardiac output syndrome (LCOS) following surgery for congenital heart disease. The LCOS is a well-recognized, frequent post-operative complication with an accepted collection of hemodynamic and physiologic aberrations. Approximately 25% of children experience a decrease in cardiac index of less than 2 L/min/m2 within 6-18 hours ...

Emergency treatment in the pediatric trauma patient with a pelvic fracture is orientated to the concepts established in adults (59). The main parameters in decision making are the hemodynamic situation and the grade of instability of the pelvis (36). It has to be considered that the child has a longer hemodynamic compensation before a severe shock state results in a potential near fatal situati...