cerebral hemodynamics (1). Neurological symptoms associated with carotid stenosis are mainly produced by thromboembolic stroke. They can be also attributed to altered cerebral hemodynamics (2). Hemodynamic factors have long been associated with the symptomatic status of stenosis, although their role is controversial (1). A percentage of patients have an insufficient collateral supply and so art...

Introduction The mechanisms responsible for the initiation and progression of cerebrovascular diseases such as ischemic stroke and aneurysms are not completely understood [1]. Previous studies have identified the hemodynamics, wall biomechanics, wall mechano-biology, and peri-vascular environment as key factors. Although their relative importance and interactions are poorly understood, hemodyna...

Cerebral hemodynamics and metabolism are frequently impaired in a wide range of neurological diseases, including traumatic brain injury and stroke, with several pathophysiological mechanisms of injury. The resultant uncoupling of cerebral blood flow and metabolism can trigger secondary brain lesions, particularly in early phases, consequently worsening the patient's outcome. Cerebral blood flow...

The abnormal, uncontrolled production of blood cells in the bone marrow causes hematological malignancies which are common and tend to have a poor prognosis. These types of cancers may alter the hemodynamics of bone marrow. Therefore, noninvasive methods that measure the hemodynamics in the bone marrow have a potential impact on the earlier diagnosis, more accurate prognosis, and in treatment m...

The heart is a sophisticated functional organ that plays a crucial role in the blood circulatory system. Hemodynamics within the heart chamber can be indicative of exert cardiac health. Due to the limitations of current cardiac imaging modalities, computational fluid dynamics (CFD) have been widely used for the purposes of cardiac function assessment and heart disease diagnosis, as they provide...

This paper describes a method that uses two cuffs to improve accuracy of blood pressure and hemodynamics estimation. A specially designed dual-cuff experimental system was used to acquire and process data from the two cuffs. The arm cuff provided cuff pressures and cuff arterial pulse waveforms. The arm cuff pulse pressure waveforms were used to compute mean arterial pressure (MAP), systolic pr...

BACKGROUND Intermittent positive-pressure ventilation (IPPV) is the "gold standard" of ventilation during cardiopulmonary resuscitation (CPR), but continuous positive airway pressure (CPAP) is increasingly discussed as an alternative. This study investigated hemodynamics and pulmonary gas exchange applying CPAP enhanced with pressure support ventilation (CPAP(PSV)) during CPR. METHODS AND RES...

OBJECTIVES The goal of this research was to study the effects of rosuvastatin on systemic and regional hemodynamics in two hypertensive rat models, one genetic, the other induced with inhibition of nitric oxide synthesis. BACKGROUND Rats naturally have low cholesterol levels that are generally unaffected by statin therapy, thus providing a good model for studying cardiovascular effects unrela...

BACKGROUND AND PURPOSE Indirect cerebral revascularization has been successfully used for treatment in Moyamoya disease and symptomatic intracranial atherosclerosis. While angiographic neovascularization has been demonstrated after surgery, measurements of local tissue perfusion are scarce and may not reflect the reported successful clinical outcomes. We investigated probabilistic independent c...

We investigated the effect of acute renal vein and hepatic vein hypertension induced by partial balloon-occlusion of the abdominal inferior vena cava (AIVC-O) and the thoracic inferior vena cava (TIVC-O) on systemic and renal hemodynamics and renal function in 13 dogs anesthetized with pentobarbital. When a renal vein pressure of 13 cm H2O was induced by AIVC-O, cardiac output, stroke volume, c...