Primary cultures of Friend virus-infected spleen cells have a marked increase of hemoglobin synthesis in vitro in the absence of added erythropoietin. Seven sulfhydryl compounds were tested in this liquid culture system and all were found to enhance hemoglobin synthesis in a dose-dependent fashion. An optimum concentration for each compound was determined beyond which inhibition was observed. T...

SUMMARY A 'switchover' from synthesis of predominantly embryonic hemoglobin to synthesis of predominantly adult hemoglobin occurs during differentiation of the house sparrow. This 'switchover' is demonstrated by a change in electrophoretic pattern generally comparable with that of the chicken, slightly different from those of the duck and man, and, perhaps, dissimilar to that of the red-wing bl...

BACKGROUND Anemia is one of the most common abnormalities in pediatric medicine. Considerable differences are seen in the peripheral blood indices of infants in developing countries. The aim of this study was to determine and compared blood hemoglobin concentration in three sites of sampling in neonate. MATERIALS AND METHODS 1600 term and preterm new infant in three sites of sampling (cord, c...

plauded for developing assay techniques for protein identification that are at least available for problematic cases and for offering their help with characteristic generosity. Needless to say, the clinical constraints are most daunting. Patients will often get sicker while waiting for a diagnosis. Therefore, on occasion, the need arises to make the best guess as to the cause of amyloid disease...

Of eight methods examined for measuring plasma hemoglobin in micromolar concentration, all exhibited acceptable linearity, reproducibility, and concurrence except when specimens were icteric or lipemic or contained methemoglobin or methemalbumin. Measurement of absorbance at 578 nm with an Allen correction permits precise assay of plasma oxyhemoglobin concentration as low as 0.01 g/L (1 mg/dL, ...

Haptoglobin is an a2 plasma glycoprotein that forms a stable complex with hemoglobin (1-5). The complex is cleared from the plasma much more rapidly than free haptoglobin so that marked hypoor anhaptoglobinemia is a concomitant of hemolysis (6, 7). Since free hemoglobin passes readily into the urine, whereas the complex, perhaps owing to its much greater size, does not, haptoglobin may play a r...

We describe, in Ethiopia, a third successful pattern of human adaptation to high-altitude hypoxia that contrasts with both the Andean "classic" (erythrocytosis with arterial hypoxemia) and the more recently identified Tibetan (normal venous hemoglobin concentration with arterial hypoxemia) patterns. A field survey of 236 Ethiopian native residents at 3,530 m (11,650 feet), 14-86 years of age, w...

Mean hemoglobin concentration of 3511 adult males derived from 19 studies of Andean male permanent residents and 10 studies of Himalayan male permanent residents were compared with reference to partial pressure of inspired oxygen. The regression equation (weighted for sample size) of PIO2 and hemoglobin concentration of the Andean miners is significantly (P less than 0.01) greater than that of ...

The intensive aquaculture needs accurate information on the identification and control of stress situations and/or diseases in order to ensure healthy fishes. The evaluation of blood parameters is the fastest way to detect stress symptoms. In this paper the hematocrit, hemoglobin concentration, mean corpuscular hemoglobin concentration (MCHC), differential count of defense cells (leucocytes and...

As light intensity increases in photoacoustic imaging, the saturation of optical absorption and the temperature dependence of the thermal expansion coefficient result in a measurable nonlinear dependence of the photoacoustic (PA) signal on the excitation pulse fluence. Here, under controlled conditions, we investigate the intensity-dependent photoacoustic signals from oxygenated and deoxygenate...