Hepatic perivascular epithelioid cell neoplasm (PEComa) is a rare type of neoplasm derived from mesenchymal tumors that is often misdiagnosed as hepatocellular carcinoma (HCC), hepatic hemangioma or other liver malignancies. The clinical and histological characteristics of PEComa have yet to be fully documented. To optimize the diagnosis and treatment of the disease, a retrospective analysis wa...

Application of cisplatin for the treatment various solid tumors is known to cause liver damage, through an increase in lipid peroxidation and reactive oxygen species production. Lycopene a powerful antioxidant agent capable preventing cells formation stronger intercellular bonds faster cellular metabolism. This study aims estimate potential lycopene induced tissue damage by studying levels seve...

Abstract Background Chronic hepatitis C virus (HCV) infection has been linked to cardiovascular disease (CVD). However, CVD risk prediction in chronic HCV-infected patients is problematic as the prevalence of different cardiac biomarkers these currently unknown. Serum lipids, which are routinely used traditional scores, may underestimate patients, while non-hepatically produced biomarkers, incl...

Polycyclic aromatic hydrocarbons (PAHs) are priority contaminants in coastal and estuarine ecosystems under anthropogenic pressure. Although PAHs tend to accumulate the sediment, toxicity for benthic flat fish such as soles may be caused by released from sediment water column. Within this context, present investigation aims at recognizing toxicopathic effects elicited after waterborne exposure ...

Metastatic lesions in the liver derived from colorectal cancer rarely invade the portal vein macroscopically. Portal vein tumor thrombus is commonly associated with hepatocellular carcinoma. Colorectal liver metastases are usually accompanied by microscopic tumor invasion into the intrahepatic portal vein, and the incidence of macroscopic tumor thrombus in the trunk of the portal vein is rare. ...

OBJECTIVE To compare the treatment outcomes of sorafenib plus transarterial chemoembolization (TACE) vs TACE alone in patients with hepatocellular carcinoma (HCC) and hepatic vein tumor thrombus (HVTT). METHODS Twenty patients who were initially diagnosed with HCC and HVTT and received TACE combined with sorafenib during February 2009 to October 2013 were included in the study. To minimize se...