OBJECTIVES The aims of this study are to investigate the prevalence of occult hepatitis B virus infection among patients with cryptogenic cirrhosis and to analyze the relationship between surface protein variability and occult hepatitis B virus infection, which may be related to the pathogenesis of occult hepatitis B virus infection in cryptogenic cirrhosis. Occult hepatitis B virus infection i...

Background and Aims: Hepatitis D virus (HDV) can infect human population either as a superinfection or concurrent hepatitis B virus (HBV) infection. It is expected that presence of HDV infection is more prevalent in endemic HBV areas. Overall 5% of Iranian general populations are chronic HBV carriers. The aim of this study was to determine the seroprevalence of HDV and its clinical impact in ...

Background and Aims: Many studies have provided evidence for the role of hepatitis B and C viruses in the development of liver cancer. Although the routine treatment is available for both conditions, no definite guideline is available to treat patients dually infected with HBV and HCV. This study was performed to determine the frequency of HBV/HCV-coinfection in Mashhad, North-East of Iran. Mat...

In patients undergoing chemotherapy for the treatment of malignant disease, the reactivation of hepatitis B virus in hepatitis B surface antigen-positive patients has been frequently reported. However, activation has also been reported in hepatitis B surface antigen-negative patients who test positive for hepatitis B core antibody and/or hepatitis B surface antibody, who were thought to have ha...

background: due to their similar routes of transmission, human immunodeficiency virus (hiv) and hepatitis b virus (hbv) co-infection occurs considerably. hbv infection progresses more rapidly in hiv-infected patients. therefore, hbv vaccination of all non-immune hiv infected patients is recommended. on the other hand, hiv-infected subjects have suboptimal responses to hbv vaccine. in this study...

Background: Hepatitis B is a health issue that become major problem worldwide with high morbidity. liver infection caused by Virus. Chronic hepatitis inflammation lasted more than 6 months and it has the potential to progress cirrhosis hepatocellular cancer. The disease influenced Gene X viral genotype. Mutations in are suspected having role progression. aim of this study was detect polymorphis...

hepatitis is the infections of a common cause disease among poly transfused patients. hepatitis c is slowed progression and inducing hcc. this study assessed hcc incidences, the role of iron and possible antitumor activity of chelators in 170 thalassemia patients using deferoxamine (dfo) therapy. they are diagnosed with hepatitis c due to positive pcr-rna. they are treated with ifn. the follow ...

BACKGROUND Cirrhosis of the liver is thought to be a major cause of morbidity and mortality in sub-Saharan Africa, but few controlled studies on the etiology of cirrhosis have been conducted in this region. OBJECTIVES We aimed to elucidate the association between environmental and infectious exposures and cirrhosis in The Gambia. METHODS Ninety-seven individuals were diagnosed with cirrhosi...

context several risk factors play the role in the development of hepatocellular carcinoma (hcc) from which chronic hepatitis b and c infections are the most important ones. dna integration of hepatitis viruses alters the function of critical genes promoting malignant transformation of virus-infected liver cells. evidence acquisition there are remarkable geographic differences in prevalence of c...