Florida is the main producer of grapefruit (Citrus paradisi Macf.) in the world. Grapefruit provide not only the traditional nutrients (carbohydrates, proteins, vitamins, minerals), but also phytochemicals such as fl avonoids, which are not essential for life, but may provide many health benefi ts. Flavanones are the dominant fl avonoids, and account for about 98% of the total fl avonoids in gr...

In a previous study we found that 50% ethanol extracts of immature fruits of Citrus unshiu (satsuma mandarin) have anti-allergic effects against the Type I, II and IV allergic reactions. However, many adverse interactions between citrus fruit, especially grapefruit juice, and drugs have been reported due to the inhibition of cytochrome P450 (CYP) activities. The purpose of this study was to exa...

Fourier transform far-infrared (FT-FIR) was exploited to evaluate the flavonoids content of orange extracts using Soxhlet extraction. The absorbance fingerprint spectra hesperidin and naringin were identified in range 0.5–7 THz. absorption peaks obtained at 1.53, 1.85, 2.46, 3.36, 4.51, 5.35, 6.51, 7.55 THz, respectively. For naringin, observed 0.75, 1.50, 2.29, 3.76, 5.18, 6.48, 8.36 perceptib...

Diabetes mellitus drugs currently available are sulfonylureas, biguanides, thiazolidines, and alpha glucoside inhibitors which widely used to control hyperglycemia. These cannot prevent complications of diabetes, these should not be continuously because it causes undesirable pathological conditions. The essential oil in lime peel is rich phenolics, especially flavonoids, can oxidative stress. T...

The anti-allergic activity of the 50% methanol extract of Citrus unshiu powder (MEC) was examined. Fifty percent methanol extract of MEC powder showed potent inhibitory activity against histamine release from basophils of patients suffering from seasonal allergic rhinitis to ceder pollen. To examine this anti-allergic mechanism in detail, we next used rat basophlilic leukemia RBL-2H3 cells. MEC...