The stability of second generation Grubbs alkylidenes to primary amines relative to the first generation derivatives is investigated. For both Grubbs alkylidene derivatives, the tricyclohexylphosphine (PCy3) ligand is displaced by n-butylACHTUNGTRENNUNGamine and diethylenetriamine. However, while displacement of PCy3 in first generation Grubbs alkylidene derivatives results in decomposition of ...

Oxo- and imido-vanadium(V) metal complexes supported by bis(phenolate)-functionalized N-heterocyclic carbene (NHC) ligands were synthesized structurally identified. In the presence of [(Ph3P)2N]Cl ([PPN]Cl), saturated NHC oxo-vanadium showed activity in coupling CO2 cyclohexene oxide (CHO) into cis-cyclohexene carbonate (cis-CHC). More importantly, complex bearing less electron-donating benzann...

Strained rings are increasingly important for the design of pharmaceutical candidates, but cross-coupling strained remains challenging. An attractive, underdeveloped, approach to diverse functionalized carbocyclic and heterocyclic frameworks containing all-carbon quaternary centers is coupling abundant strained-ring carboxylic acids with aryl halides. Herein we disclose development a nickel-cat...

Amide synthesis is one of the most crucial transformations in chemistry and biology. Among various catalytic systems, N-heterocyclic carbene (NHC)-based ruthenium (Ru) catalyst systems have been proven to be active for direct amides by sustainable acceptorless dehydrogenative Coupling primary alcohols with amines. Most often, these usually use monodentate NHC thus require an additional ligand o...

Oxidative addition of cobaltoceniumdiazonium bis(hexafluoridophosphate) with (pseudo)halide aurates gave gold(III) complexes containing zwitterionic cobaltoceniumide as a ligand. Its selenium derivative, cobaltoceniumselenolate, was obtained by an electrophilic aromatic substitution reaction of iodocobaltocenium iodide with Na2 Se. Spectroscopic and structural data in combination with DFT calcu...

The terphspan scaffold was employed to support a bis(N-heterocyclic carbene) ligand () that provides a m-terphenyl canopy over one side of its metal complexes. Single-crystal X-ray diffraction studies on a silver complex of {[Ag()]AgBr(2)}(2) revealed an unusual tetranuclear silver core with a Ag-Ag bond distance of 3.0241(8) A with as a trans-chelating ligand (C-Ag-C = 171 degrees ). A prelimi...

3-Hydroxypy rid ine-2-carboxaldehyf le thiosemicarbazone (3-HP) has been shown to be active against leukemia L1210, Ehrlich ascites carcinoma, lym]>homa L5178Y, the Lewis lung carcinoma, and adenocarcinoma 755. 3-HP is active, in some in stances, by gavage and also by delayed treatment. 3-HP is a member of a broad class of a-(.Y)-heterocyclic carboxaldehyde thiosemicarbazones, several of which ...

Two ruthenium-based pre-catalysts containing an ionic tag covalently connected to a N-heterocyclic carbene (NHC) ligand are reported. These novel complexes, bearing a polar benzimidazolium group, are air-stable and can be easily prepared from commercially available reagents. The quaternary benzimidazolium tag allows the efficient separation of ruthenium waste from the metathesis product after r...

The reactions of f-block silylamido N-heterocyclic carbene (NHC) complexes ([M(L)(N{SiMe(3)}(2))(2)], M = Y, Ce, and U, L = bidentate alkoxy-tethered NHC ligand) with CO and CO(2) have been studied and compared to each other, to those of selected [M(L)(2)(N{SiMe(3)}(2))] complexes, and to those of [M(N{SiMe(3)}(2))(3)] to identify the effect of the labile NHC group on the small molecule activat...

In the title compound, [Hg(C(42)H(38)N(4)O(2))](PF(6))(2)·2CH(3)CN, the Hg(II) cation lies on a twofold axis which is also the inter-nal symmetry element of the complete cationic complex. The Hg(II) cation is coordinated by two symmetry-related C(carbene) atoms [Hg-C = 2.058 (9) Å] in a nearly linear geometry, with a C-Hg-C angle of 175.8 (5)°. There are weak inter-molecular C-H⋯F inter-actions...