OBJECTIVE To determine whether challenging behavior in young children with autism and other developmental disabilities can be treated successfully at lower cost by using telehealth to train parents to implement applied behavior analysis (ABA). METHODS We compared data on the outcomes and costs for implementing evidence-based ABA procedures to reduce problem behavior by using 3 service deliver...

Impairments in social and emotional skills are a defining feature of autism spectrum disorder. Recent research shows that structural and functional abnormalities within the neural system that matches observation and execution of actions--the mirror neuron system--may explain the social aspects of the pathophysiology of autism spectrum disorder.

The “FRIDA” framework is a guide for the agile development of accessible software users with Autism Spectrum Disorder (ASD), as tool strengthening emotional and social skills in treatment autism. It based on use skills, designed focus user intellectual disabilities. A mixed quasi-experimental study carried out three groups: children ASD, expert therapists ASD treatments designers adapting Desig...

BACKGROUND Autism is a neurodevelopmental disorder of unknown etiopathogenesis associated with structural and functional abnormalities of neurons and increased formation of reactive oxygen species. Our previous study revealed enhanced accumulation of amino-terminally truncated amyloid-β (Aβ) in brain neurons and glia in children and adults with autism. Verification of the hypothesis that intran...

Atypical activation during the Embedded Figures Task has been demonstrated in autism, but has not been investigated in siblings or related to measures of clinical severity. We identified atypical activation during the Embedded Figures Task in participants with autism and unaffected siblings compared with control subjects in a number of temporal and frontal brain regions. Autism and sibling grou...

In the hope of discovering early markers of autism, attention has recently turned to the study of infants at risk owing to being the younger siblings of children with autism. Because the condition is highly heritable, later-born siblings of diagnosed children are at substantially higher risk for developing autism or the broader autism phenotype than the general population. Currently, there are ...

Background: In education, Information and Communication Technology (ICT) has gone from being a convenient option to permanent necessity. For students people with functional diversity, it is of seminal importance. It therefore worth learning how professionals perceive digital tools apps for diversity autism: its requirements potential. As no instrument measure this exists, we have designed quest...

Autism is a highly heritable neurodevelopmental disorder, yet the genetic underpinnings of the disorder are largely unknown. Aberrant brain overgrowth is a well-replicated observation in the autism literature; but association, linkage, and expression studies have not identified genetic factors that explain this trajectory. Few studies have had sufficient statistical power to investigate whole-g...