نتایج جستجو برای: high level resistant

تعداد نتایج: 2991632  

2015
Bahman Mirzaei Zakaria Bameri Ryhane Babaei Fereshteh Shahcheraghi

BACKGROUND Bordetella pertussis, as a causative agent of whooping cough, due to the annual rise y of infection cases, failure of prophylaxis and treatment by macrolides, is considered as the new concern in the health care system. OBJECTIVES The main objective of this study was the determination of single nucleotide polymorphisms (SNPs) at domain V, as the main binding site for macrolides, fol...

Journal: :The Journal of antimicrobial chemotherapy 2004
Mihaela Peric Bülent Bozdogan Chad Galderisi Dan Krissinger Terry Rager Peter C Appelbaum

BACKGROUND Haemophilus influenzae HMC-C with high-level macrolide resistance after multi-step selection by clarithromycin reverted spontaneously and became hypersusceptible to macrolides. OBJECTIVE Determination of macrolide resistance mechanism(s) in hypersusceptible and hyperresistant strains. METHODS The presence of macrolide efflux in the strains was studied by radioactive erythromycin ...

Journal: :Emergency Medicine Journal 2000

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