In the recent years, intensive research work has been dedicated to prove conditional lower bounds in order to reveal the inner structure of the class P. These conditional lower bounds are based on many popular conjectures on well-studied problems. One of the most heavily used conjectures is the celebrated Strong Exponential Time Hypothesis (SETH). It turns out that conditional hardness proved b...

One of the mechanisms of cisplatin cell cytotoxicity is the mitochondria-associated induction of apoptosis. The morphological or functional change of mitochondria in cisplatin-resistant cells has already been reported. Herein we present additional data describing the mitochondrial genomic and functional changes in cisplatin- resistant cells. Cisplatin increased the level of apoptotic cells in c...

On utilizing the spectral representation of selfadjoint operators in Hilbert spaces, some error bounds in approximating $n$-time differentiable functions of selfadjoint operators in Hilbert Spaces via a Taylor's type expansion are given.

IntroductionOverweight (ov) and obesity (ob) are conditions associated with excess adipose tissue mass. Overweight obese (ov/ob) individuals at an increased risk for chronic complications like diabetes mellitus, cardiovascular disease, liver malignancies, sleep apnoea, osteoarthritis, urinary incontinence, psychosocial issues. The prevalence of ov/ob is increasing globally in South Asia. This r...

in this paper some new applications of empirical mode decomposition (emd) and hilbert spectrum in seismic ground-roll attenuation, random noise attenuation and spectral decomposition are introduced. hilbert spectrum is a time-frequency representation for hilbert-huang transform which is obtained by combination of instantaneous frequency (if) concept and intrinsic mode function of empirical mode...

The invariant Hilbert schemes considered in [4] were proved to be affine spaces. The proof relied on the classification of strict wonderful varieties. We obtain in the present article a classification-free proof of the affinity of these invariant Hilbert scheme by means of deformation theoretical arguments. As a consequence we recover in a shorter way the classification of strict wonderful vari...

Ovarian cancer (OV) is the most common gynaecological worldwide. Immunotherapy has recently been proven to be an effective treatment strategy. The work here attempts produce a prognostic immune-related gene pair (IRGP) signature estimate OV patient survival. Gene Expression Omnibus (GEO) and Cancer Genome Atlas (TCGA) databases provided genetic expression profiles clinical data of patients. Bas...

BACKGROUND Recurrent non-medullary thyroid carcinoma (NMTC) is a rare disease. We initially characterized 27 recurrent NMTC: 13 papillary thyroid cancers (PTC), 10 oncocytic follicular carcinomas (FTC-OV), and 4 non-oncocytic follicular carcinomas (FTC). A validation cohort composed of benign and malignant (both recurrent and non-recurrent) thyroid tumours was subsequently analysed (n = 20). ...

Serpin superfamily proteins, most of which are serine protease inhibitors, share an unusual mechanism rooted in their conserved metastable tertiary structure. Although serpins have been identified in isolated members of archea, bacteria, and plants, a remarkable expansion is found in vertebrates. The chicken protein ovalbumin, a storage protein from egg white, lacking protease inhibitory activi...

on utilizing the spectral representation of selfadjoint operators in hilbert spaces, some error bounds in approximating $n$-time differentiable functions of selfadjoint operators in hilbert spaces via a taylor's type expansion are given.