This is "Tony" Pearse's last solo book (by his printed admission) in histochemistry. 'Tis easy to feel quite touched and sentimental about his current effort, especially emanating from an Emeritus Professor. His fourth edition, now three books, certainly reflects a history of the field. All his volumes have, in their time, offered a major contribution. Certainly, on each occasion, nothing has c...

The retina is not only an exceedingly interesting structure in its own right, but it presents an exceptional opportunity for study of the central nervous system, of which it is an integral part. In the retina a number of nervous elements which are usually intimately mixed together have been sorted out into discrete layers. Analysis of each of these layers could provide information as to the com...

Using a new NMR correlation-peak imaging technique, we were able to investigate noninvasively the spatial distribution of carbohydrates and amino acids in the hypocotyl of castor bean seedlings. In addition to the expected high sucrose concentration in the phloem area of the vascular bundles, we could also observe high levels of sucrose in the cortex parenchyma, but low levels in the pith paren...

Histochemical techniques were used to study the postnatal muscle fibre differentiation patterns in the plantaris and soleus muscles of male Sprague-Dawley rats. Nine groups of animals (n = 6/group) were killed at 1, 6, 11, 16, 21, 26, 31, 36, and 140 days of age. Serial transverse sections of the two muscles were stained with H & E, NADH-D, and myofibrillar ATPase with acid (pH 4.35) or alkali ...

Lectin peroxidase histochemical analysis was carried out on pancreatic tissue from patients with pancreatic carcinoma and chronic pancreatitis and from subjects with normal pancreas to find a tumour specific pattern of lectin binding that would aid histological and cytological diagnosis. There were striking differences between the lectin binding characteristics of the different cell types in th...

For some years in this laboratory the principles and methods of quantitative histochemistry introduced by Linderstr#{216}m-Lang and loiter (7, 10) have been used for studies on the chemical pathology of the nervous system. A particular effort has been made to describe the biochemical architecture of rat and human cerebral cortex, primarily because of its intrinsic neurological importance and th...

Histochemistry continues to be widely applied in biomedical research, being nowadays mostly addressed to detect and locate single molecules or molecular complexes inside cells and tissues, and to relate structural organization and function at the high resolution of the more advanced microscopical techniques. In the attempt to see whether histochemical novelties may be found in the recent litera...