BACKGROUND The genetic basis of postzygotic isolation is a central puzzle in evolutionary biology. Evolutionary forces causing hybrid sterility or inviability act on the responsible genes while they still are polymorphic, thus we have to study these traits as they arise, before isolation is complete. METHODOLOGY/PRINCIPAL FINDINGS Isofemale strains of D. mojavensis vary significantly in their...

Coupling chromatin immunoprecipitation (ChIP) with recently developed massively parallel sequencing technologies has enabled genome-wide detection of protein-DNA interactions with unprecedented sensitivity and specificity. This new technology, ChIP-Seq, presents opportunities for in-depth analysis of transcription regulation. In this study, we explore the value of using ChIP-Seq data to better ...

Mechanical signals of both low and high intensity are inhibitory to fat and anabolic to bone in vivo, and have been shown to directly affect mesenchymal stem cell pools from which fat and bone precursors emerge. To identify an idealized mechanical regimen which can regulate MSC fate, low intensity vibration (LIV; <10 microstrain, 90 Hz) and high magnitude strain (HMS; 20,000 microstrain, 0.17 H...

This present paper was focused on the manufacture of activated carbon (AC) and its application in the electrokinetic remediation (EKR) technology on removal of the heavy metals (HMs) from the municipal solid waste incineration fly ash. AC was produced from Neosinocalamus affinis (NF) by chemical activation with H3PO4 in N2 atmosphere, the effects of activation temperatures, soaking time and imp...

Risk-based assessment is a way to evaluate the potential hazards of contaminated sites and is based on considering linkages between pollution sources, pathways, and receptors. These linkages can be broken by source reduction, pathway management, and modifying exposure of the receptors. In Taiwan, the Soil and Groundwater Pollution Remediation Act (SGWPR Act) uses one target regulation to evalua...

Pregnancy is associated with changes in host susceptibility to infections and inflammatory disease. We hypothesize that metabolic enzyme trafficking affects maternal neutrophil activation. Specifically, immunofluorescence microscopy has shown that glucose-6-phosphate dehydrogenase (G-6-PDase), the rate-controlling step of the hexose monophosphate shunt (HMS), is located near the cell periphery ...

Aqueous humor is known to contain a significant level of H2O2, but the mechanisms by which ocular tissues protect against oxidative damage are not well understood. With the use of C-1-, C-2-, and C-6-labeled glucose, the contribution of glutathione (GSH) metabolism and the hexose monophosphate shunt (HMS) to the detoxification of peroxide in the lens has been evaluated. It was observed that H2O...

As collaboration in creating software systems becomes more complex and frequent among multidisciplinary teams, finding new strategies to support this collaboration becomes crucial. The challenge is to bridge the communication gaps among stakeholders with diverse cultural and professional backgrounds. Moreover, future uses and issues cannot be completely anticipated at design time, and it is nec...

Fixed assets have an important role for the smooth running of cooperative operations. Proper policy in treatment fixed asset accounting is needed maximizing that role. Users financial statements urgently need information accordance with Financial Accounting Standards Entities Without Public Accountability (SAK ETAP) so analysis needs to be done ensure whether has been ETAP SAK. The data used se...

Abstract The Yellow River Estuary (YRE) and adjacent Laizhou Bay (LB) encounter eco-environmental risks caused by heavy metals (HMs) pollution. Here magnetic measurements were performed on 239 surface sediment samples from the YRE LB to establish a rapid effective method for detecting HMs. Magnetite, maghemite, hematite coexist in sediments. distributions of minerals are dominated sources (Yell...