ABSTRACT: Transmissible spongiform encephalopathies are neurodegenerative diseases that affect several mammalian species. Bovine spongiform encephalopathy (BSE) is among the mentioned diseases in cattle caused by abnormally fold prion proteins. Polymorphisms of the prion protein gene (PRNP) have been shown to be major determinations for the susceptibility to transmitted perion diseases in human...

Progeny of Holstein females mated to sires of different breeds were genetically evaluated along with their purebred Holstein contemporaries born in the same herds using multiple trait animal models. The resulting estimated breeding values (EBV) of cows were averaged within breed of sire and compared relative to progeny of purebred Holstein sires for various economic traits. All progeny were bor...

A total of 5,909 scrotal circumference and 5,373 tesricular consistency (tonometer) measurements were made on Holstein bulls in seven artificial insemination studs. Comparable measurements were made on 339Angus bulls. The multiple regression equation, Y = -4.67 + 47.26 log X 1 1 . 7 4 (log X)2), where ~f is scrotal circumference in cm and X is bull age in months, described the high rate of test...

BACKGROUND Cholesterol deficiency (CD), a newly identified autosomal recessive genetic defect in Holstein cattle, is associated with clinical signs of diarrhea, failure to thrive, and hypocholesterolemia. HYPOTHESIS/OBJECTIVES The objective is to describe the clinicopathological phenotype of affected Holstein cattle homozygous for the causative apolipoprotein B gene (APOB) mutation. ANIMALS...

The objective of this study was to determine the accuracy of prediction of body weight from body measurements in beef cattle. Wither height, chest girth, body length, chest depth, hip width and hip height measurements were obtained from Holstein, Brown Swiss and crossbred (n=140). Determination coefficients (R2) of regression equation that included all body measurements were higher in Brown Swi...

A main goal of cattle genomics is to identify DNA differences that account for variations in economically important traits. In this study, we performed whole-genome analyses of three important cattle breeds in Korea--Hanwoo, Jeju Heugu, and Korean Holstein--using the Illumina HiSeq 2000 sequencing platform. We achieved 25.5-, 29.6-, and 29.5-fold coverage of the Hanwoo, Jeju Heugu, and Korean H...