BACKGROUND Hyperfibrinolysis (HF) is a major contributor to coagulopathy and mortality in trauma patients. This study investigated (i) the rate of HF during the pre-hospital management of patients with multiple injuries and (ii) the effects of pre-hospital tranexamic acid (TxA) administration on the coagulation system. METHODS From 27 trauma patients with pre-hospital an estimated injury seve...

BACKGROUND Parkinson's disease patients are more likely to be hospitalized, have higher rates of hospital complications, and have an increased risk of deterioration during hospitalization. Length of stay is an important underlying factor for these increased risks. We aimed to investigate potential medication errors that may occur during hospitalization and its impact on length of hospital stay....

Abstract Background Caregivers’ knowledge, practice and adherence in medication administration who care for children with chronic illness requiring long-term pharmacological treatments are factors associating safety at home. This study aimed to determine the medication-related among caregivers of chronically ill Malaysia. cross-sectional was conducted paediatric outpatient clinic a tertiary pub...

The objective of the study : to compare changes in blood level C-reactive protein (CRP) during administration different formulations tocilizumab (TCZ) COVID-19 patients admitted hospital real clinical practice. Subjects and methods . cohort 14 was included retrospective study; they all had a severe course were hospital: 7 received intravenous infusions subcutaneous injections. indication for pr...

The increase in healthcare costs is a source of concern in most health systems, and the adoption of measures to control costs is at the center of current health policies in most European countries. Efficiency has become a key concern for hospital managers, who are under pressure to provide more services at a lower cost. Associated with this concern, there is an increasing interest of hospital m...

Chemotherapy medication errors may lead to potentially harmful consequences while most of them could be preventable. This study aims to determine the incidence and type of drug handling and administration errors among the nurses and to identify possible contributing factors. Setting of the study was a teaching hospital affiliated to Shahid Beheshti University of Medic...

Veterans Administration Hospital, San Diego, California 92161 (H. T. W., J. 5.1; University of California, San Diego, School of Medicine, Department of Pathology, San Diego, California 92037 (H. T. W.J; Veterans Administration Hospital, San Antonio, Texas 78284 (S. H.J; University of San Antonio Medical School,SanAntonio, Texas78284(S. H.J;Universityof California,SantaCruz, Departmentof Biology...

A 54-year-old woman presented to hospital after deliberate acute ingestion of paracetamol 20 g. Despite early administration of a standardised acetylcysteine regimen, the patient developed acute liver impairment and acute renal impairment. Prolonged acetylcysteine administration and supportive measures allowed restoration of normal liver and renal function. Early presentation to hospital and pr...

STUDY OBJECTIVE The variable effectiveness of clinical asthma pathways to reduce hospital admissions may be explained in part by the timing of systemic corticosteroid administration. We examine the effect of early (within 60 minutes [SD 15 minutes] of triage) versus delayed (>75 minutes) administration of systemic corticosteroids on health outcomes. METHODS We conducted a prospective observat...

conclusions the frequency of nis in this hospital was lower in comparison with other worldwide studies. however, low incidence of health care-associated infections in our study may be due to under diagnosis and underreporting of such infections by health care staff. results the incidence of nis was low (i.e. < 2%). among 16936 admitted patients in this hospital, 174 patients (79 males and 95 fe...