Increased reactivity to stress is observed in patients with schizophrenia spectrum disorders and their healthy siblings in comparison to the general population. Additionally, higher levels of neuroticism, as a proposed psychological measure of stress sensitivity, increasethe risk for schizophrenia. HPA axis dysregulation is one of the possible mechanisms related to the vulnerability-stress mode...

Introduction Recent studies report a prevalence of comorbid anxiety disorder 38% and 80% sleep disorders in schizophrenia. Insomnia has been associated with worsening psychopathological symptoms increased hospitalization rates. Objectives The aim our work was to review mechanisms action the use benzodiazepines, GABAergic drugs melatonin for treatment insomnia Methods We carried out narrative fo...

BACKGROUND Schizophrenia is a chronic mental health disorder associated with increased hospital admissions and excessive utilization of outpatient services and long-term care. This analysis examined health care resource utilization from a 24-month observational study of patients with schizophrenia initiated on risperidone long-acting therapy (RLAT). METHODS Schizophrenia Outcomes Utilization ...

OBJECTIVE Magnetic resonance imaging (MRI) studies of schizophrenia reveal temporal lobe structural brain abnormalities in the superior temporal gyrus and the amygdala-hippocampal complex. However, the middle and inferior temporal gyri have received little investigation, especially in first-episode schizophrenia. METHOD High-spatial-resolution MRI was used to measure gray matter volume in the...

Purpose: Individuals with schizophrenia have a vastly reduced lifespan compared with the general population; comorbid cardiovascular disease (CVD) is the leading cause of death for them. Furthermore, these individuals are more likely to have metabolic syndrome-related disorders (MSDs), which increase CVD risk. We examined the medical records of long-term inpatients with schizophrenia to identif...

objective: the relationship between obsessive compulsive disorder and schizophrenia has been a matter of dispute for ages. this study aimed to investigate the differences between schizophrenia with obsessive compulsive symptoms (ocs) and schizophrenia without ocs in affecting positive and negative symptoms of schizophrenia.  methods: study participants comprised 30 patients with schizophrenia w...

Purpose: Individuals with schizophrenia have a vastly reduced lifespan compared with the general population; comorbid cardiovascular disease (CVD) is the leading cause of death for them. Furthermore, these individuals are more likely to have metabolic syndrome-related disorders (MSDs), which increase CVD risk. We examined the medical records of long-term inpatients with schizophrenia to identif...

Purpose: Individuals with schizophrenia have a vastly reduced lifespan compared with the general population; comorbid cardiovascular disease (CVD) is the leading cause of death for them. Furthermore, these individuals are more likely to have metabolic syndrome-related disorders (MSDs), which increase CVD risk. We examined the medical records of long-term inpatients with schizophrenia to identif...

BACKGROUND Schizophrenia is associated with central (sagittal) midline reductions of the P300 cognitive event-related potential and topographic asymmetry of P300, with reduced left temporal voltage. This P300 asymmetry is, in turn, linked to tissue volume asymmetry in the posterior superior temporal gyrus. However, it is unknown whether P300 asymmetry is specific to schizophrenia and whether ce...