Verticillium wilt, caused by soil-borne fungi of the genus Verticillium, is an economically important disease that affects a wide range of host plants. Unfortunately, host resistance against Verticillium wilts is not available for many plant species, and the disease is notoriously difficult to combat. Host-induced gene silencing (HIGS) is an RNA interference (RNAi)-based process in which small ...

Group A Streptococcus (Streptococcus pyogenes), group B Streptococcus (Streptococcus agalactiae) and Streptococcus pneumoniae (pneumococcus) are host-adapted bacterial pathogens among the leading infectious causes of human morbidity and mortality. These microbes and related members of the genus Streptococcus produce an array of toxins that act against human cells or tissues, resulting in impair...

Healthy individuals live in peaceful co-existence with an immense load of intestinal bacteria. This symbiosis is advantageous for both the host and the bacteria. For the host it provides access to otherwise undigestible nutrients and colonization resistance against pathogens. In return the bacteria receive an excellent nutrient habitat. The mucosal immune adaptations to the presence of this com...

Ectoparasites can be significant pests for the poultry industry. The chicken (or poultry) red mite and the northern fowl mite are the most economically important ectoparasites of poultry globally. These mites can have significant deleterious effects on its fowl host including anaemia, reduced egg production, and egg quality. The chicken mites may also act as a vector for pathogens. Molecular bi...

Catheter-associated infections can cause severe complications and even death. Effective antimicrobial modification of catheters that can prevent device colonization has the potential of preventing clinical infection. We studied in vitro the antimicrobial activities of central venous catheters impregnated with N-acetylcysteine (NAC), an antibiofilm agent, and a broad-spectrum antibiotic against ...

Mutualistic ants are commonly considered as an efficient indirect defence against herbivores. Nevertheless, their indirect protective role against plant pathogens has been scarcely investigated. We compared the protective role against pathogens of two different ant partners, a mutualistic and a parasitic ant, on the host plant Acacia hindsii (Fabaceae). The epiphytic bacterial community on leav...

RNA silencing is a conserved mechanism in eukaryotes that plays an important role in various biological processes including regulation of gene expression. RNA silencing also plays a role in genome stability and protects plants against invading nucleic acids such as transgenes and viruses. Recently, RNA silencing has been found to play a role in defence against bacterial plant pathogens in Arabi...

The production of low-molecular-weight antimicrobial molecules within plants is one component of defense against pathogens. Among them, preformed antimicrobial compounds (phytoanticipins) are the first biochemical barriers against pathogens. Saponins (a group of phytoanticipins) are present constitutively in plants and play important roles in plant defense. A variety of biological roles have be...

Chemically managed plants impose environmental risks to humans and environment. Using biological approaches control plant diseases is a more effective environment friendly alternative. The approach disease refers controlling by using organisms like fungi, bacteria viruses. This can be done introduction or utilization of resident antagonistic living organisms. Biological achieved through differe...

BACKGROUND Although the plant microbiome is crucial for plant health, little is known about the significance of the seed microbiome. Here, we studied indigenous bacterial communities associated with the seeds in different cultivars of oilseed rape and their interactions with symbiotic and pathogenic microorganisms. RESULTS We found a high bacterial diversity expressed by tight bacterial co-oc...