Many common diseases have an important inflammatory component mediated in part by macrophages. Here we used a systems genetics strategy to examine the role of common genetic variation in macrophage responses to inflammatory stimuli. We examined genome-wide transcript levels in macrophages from 92 strains of the Hybrid Mouse Diversity Panel. We exposed macrophages to control media, bacterial lip...

We evaluate thermodynamical quantities and transport coefficients of a dense and hot hadronic matter based on an event generator URASiMA (Ultra-Relativistic AA collision Simulator based on Multiple Scattering Algorithm). The statistical ensembles in equilibrium with fixed temperature and chemical potential are generated by imposing periodic boundary condition to the simulation of URASiMA, where...

The objective of the present study was to evaluate the effect of sintering condition on matrix formation and subsequent drug release from polymer matrix tablet for controlled release. The present study highlights the use of a microwave oven for the sintering process in order to achieve more uniform heat distribution with reduction in time required for sintering. We could achieve effective sinte...

Critical initial conditions for thermal ignition are calculated numerically for planar, cylindrical and spherical geometries. In each case a comparison is made on the bifurcation diagram with the intermediate steady state(s). It is clearly seen that the actual critical initial condition which depends upon the initial temperature proÐle, is partly below the intermediate steady state(s). The vari...

The predominant microorganisms in samples taken from shower heads in residences in the Korean city "N" were Stenotrophomonas maltophilia, Sphingomonas paucimobilis, Acidovorax temperans, and Microbacterium lacticum. Legionella was not detected in this case. The volatile organic compounds (VOCs) vinylacetate, NN-DMA, cis-1,2-dichloroethylene, epichlorohydrin, and styrene were measured in five ty...

The broken efficiency of cell wall and the release amount of Pichia pastoris intracellular protein under different cell breaking conditions were investigated in this paper. The results showed that broken efficiency using hot alkali combined with high-pressure homogenizing method was higher than that of enzyme hydrolysis, hot alkali treatment and high-pressure homogenation, respectively. Suspend...

background and objectives: prunus domestica (plum) has been considered as a useful remedy for several disorders in iranian traditional medicine (itm). it has cold and wet temperament and is used as syrup for hot temperament diseases such as hot headache and stomach disorders. in the present study, plum syrup has been formulated according to itm manuscripts and quality control evaluations have b...

sensitivity of tomato fruits to chilling injury limits its storage and marketability. this study investigated the effect of hot water treatment (hwt) on reducing the consequences of chilling injury (ci) with respect to quality attributes of tomatoes during storage. tomatoes were harvested at three ripening stages: mature green, pink, and red; dipped in hot water at 45°c for 15 min; and stored a...

Spices are the most attractive ingredients to confer an authentic taste to food. As they are derived from plants, they harbour allergenic potency and can induce symptoms ranging from mild local to severe systemic reactions. Due to the content of pharmacologically active substances of spices, the diagnosis of allergy and the differentiation from intolerance reactions may be difficult. Associatio...