نتایج جستجو برای: hoxa10

تعداد نتایج: 288  

Journal: :journal of reproduction and infertility 0

endometriosis is a gynecologic disorder characterized by the presence of viable, extrauterine endometrial tissue, predominantly on the ovary and pelvic peritoneum (1-3). typical symptoms consist of pelvic pain, dysmenorrhea, and infertility (1, 2). this condition takes place only in women of menstrual age, can grow or bleed cyclically and may cause adhesions (1, 2). endometriosis represents a w...

Journal: :Fertility and Sterility 2021

ObjectiveTo study the effect of human plasma from different sources, namely, umbilical cord blood and adult platelet-rich (PRP), on regeneration endometrial damage.DesignComposition analysis, in vitro approaches, a preclinical murine model using to promote regeneration.SettingHospital university laboratories.Patient(s)/Animal(s)Adult four Asherman syndrome/endometrial atrophy patients one ferti...

Journal: :Blood 2008
Vijay P S Rawat Silvia Thoene Vegi M Naidu Natalia Arseni Bernhard Heilmeier Klaus Metzeler Konstantin Petropoulos Aniruddha Deshpande Leticia Quintanilla-Martinez Stefan K Bohlander Karsten Spiekermann Wolfgang Hiddemann Michaela Feuring-Buske Christian Buske

The mechanisms underlying deregulation of HOX gene expression in AML are poorly understood. The ParaHox gene CDX2 was shown to act as positive upstream regulator of several HOX genes. In this study, constitutive expression of Cdx2 caused perturbation of leukemogenic Hox genes such as Hoxa10 and Hoxb8 in murine hematopoietic progenitors. Deletion of the N-terminal domain of Cdx2 abrogated its ab...

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