The Health Services Research & Development Service (HSR&D) focuses on identifying effective and cost-effective strategies for organizing and delivering health care and for optimizing patient and system-level outcomes. HSR&D programs span the continuum of health care research and delivery, from basic research to the dissemination of research results, and ultimately to the application of these fi...

In plants, the heat stress response (HSR) is highly conserved and involves multiple pathways, regulatory networks and cellular compartments. At least four putative sensors have recently been proposed to trigger the HSR. They include a plasma membrane channel that initiates an inward calcium flux, a histone sensor in the nucleus, and two unfolded protein sensors in the endoplasmic reticulum and ...

In this paper we present a hierarchical routing protocol in a large wireless, mobile network such as found in the automated battle field or in extensive disaster recovery operations. Conventional routing does not scale well to network size. Likewise, conventional hierarchical routing cannot handle mobility eficiently. We propose a novel soft state wireless hierarchical routing protocol Hierarch...

A comparison between automatic speech recognition (ASR) and human speech recognition (HSR) is performed as prerequisite for identifying sources of errors and improving feature extraction in ASR. HSR and ASR experiments are carried out with the same logatome database which consists of nonsense syllables. Two different kinds of signals are presented to human listeners: First, noisy speech samples...

Two human neuroendocrine tumor cell lines derived from a colon carcinoma contain either numerous double minute chromosomes (COLO 320 DM) or a homogeneously staining marker chromosome (COLO 320 HSR). We found amplification and enhanced expression of the cellular oncogene c-myc in both COLO 320 DM and HSR cells, and we were able to show that the homogeneously staining regions of the COLO 320 HSR ...

Barriers have been identified in the literature to the implementation of evidence-based practice in dentistry. A major concern is the lack of rigorous evidence for clinical practices. Little attention has been given to the lack of rigorous health services research. Evidence-based practice is more about effectiveness than efficacy and will influence the type of research that characterizes health...

This study analyzed Chinese labor-force survey data to determine the relationship between cropland abandonment and high-speed rail (HSR) infrastructure. A PSM-DID approach was employed examine 2014 2016 from China Labor-force Dynamics Survey estimate impact of HSR, which it found that HSR accessibility promoted in local farm households with a coefficient 0.206, is, projects led 20.6% increase a...

Using an Italian land use conflict on the building a high-speed railway (HSR) as case study, we analyzed how perceived changes in public opinion influence (a) people’s willingness to speak out, and (b) subsequently their intentions engage action (N = 311). Regardless of whether they were majority or minority side conflict, citizens’ out was positively associated with perceptions that position b...

In Caenorhabditis elegans, the programmed repression of the heat shock response (HSR) accompanies the transition to reproductive maturity, leaving cells vulnerable to environmental stress and protein aggregation with age. To identify the factors driving this event, we performed an unbiased genetic screen for suppressors of stress resistance and identified the mitochondrial electron transport ch...

Increased infection rates in burned patients may result from a disproportionate increase in the suppressor subpopulations. Measurement of lymphocyte subpopulations is difficult in burned patients because gradient-purified cells are contaminated by nonlymphoid cells. The accuracy of flow cytometric subpopulation analysis was improved by restricting (gating) the analysis to cells with light-scatt...