In 1966 F. J. Inglefinger, A. S. Relman, and M. Finland published a book Controversy in Internal Medicine.' Even at that late date, the authors of one of the chapters vigorously defended the position that the drug treatment of essential hypertension was of no benefit. The question was hotly debated during the 1950s and 1960s. In fact, many authorities strongly opposed such treatment, arguing th...