Supernumerary teeth are teeth that are present in addition to normal teeth. Although several hypotheses and some molecular signalling pathways explain the formation of supernumerary teeth, but their exact disease pathogenesis is unknown. To study the molecular mechanisms of supernumerary tooth-related syndrome (Gardner syndrome), a deeper understanding of the aetiology of supernumerary teeth an...

Large-scale genomic analyses of ancient human populations have become feasible partly due to refined sampling methods. The inner part of petrous bones and the cementum layer in teeth roots are currently recognized as the best substrates for such research. We present a comparative analysis of DNA preservation in these two substrates obtained from the same human skulls, across a range of differen...

Objectives: In restorative dentistry, it is essential to estimate the amount of remnant tooth structure after caries removal to make the best treatment plan. The present study was aimed to determine whether there is a correlation between the real thickness of remnant dentin under carious lesion and the radiographical measurement from photostimulable phosphor plates (PSPs). Methods: a whole numb...

Objectives: This study aimed to assess tooth discoloration at 6 months following the use of 5% fluoride varnish (Duraflur), AH 26, zinc oxide eugenol (ZOE)-based sealer and mineral trioxide aggregate (MTA)-based sealer in extracted premolars. Materials and Methods: In this in vitro, experimental study, 75 freshly-extracted human premolars with completely formed roots underwent root canal treat...

tooth discoloration induced by endodontic sealers, is a common finding that impairs aesthetic outcome of endodontic treatment. the aim of the present mini literature review, was to summarize the existing data on discoloration potential of different endodontic sealers. the research covered the article published in pubmed and google scholar from 2000 to 2015. the searched keywords included ‘tooth...

Segmentation of tooth/teeth from dental computed tomography (CT) or X-ray images and thereby its 3D visualization is of great significance for computed assistance strategies such as anomalies detection, planning for orthodontics, dental implants, face and jaw surgeries and much more. This application is often used in forensic science for human identification using matching of post-mortem (PM) a...

We have used synchrotron x-ray diffraction to study the crystal orientation in human dental enamel as a function of position within intact tooth sections. Keeping tooth sections intact has allowed us to construct 2D and 3D spatial distribution maps of the magnitude and orientation of texture in dental enamel. We have found that the enamel crystallites are most highly aligned at the expected occ...

Odontogenic cysts are pathological cavities enclosed by fibrous connective tissue and lined with epithelial that develops from odontogenic tissues in the maxilla mandible's tooth-bearing regions. Trauma or tooth caries is main cause of radicular periapical cysts. Pulp necrosis outcome dental irritating pulp cavity. Once infection has reached root's tip, it causes periodontitis, which may lead t...

Tooth agenesis is one of the most common anomalies of human dentition. Recent genetic studies have provided information regarding a number of genes related to both syndromic and non-syndromic forms of hypodontia. In a previous study, we found that polymorphism in rs11001553 of DKK1 was associated with hypodontia in the Chinese Han population. In this study, we extended this investigation to 89 ...

Objective: This study was designed to compare the relative efficiency of GC, Tooth Mousse, which contains 10% ACP-CPP and GC Tooth Mousse Plus which contains amorphous calcium phosphate casein phosphopeptide (ACP-CPP) with sodium fluoride 0.2% w/w (900 ppm) to inhibit enamel demineralization adjacent to orthodontic brackets in vitro. Materials and methods: Forty-five non-carious, human maxillar...