Inverse chaotic resonance is a phenomenon in which the neuronal mean firing rate exhibits minimum with respect to activity. In this paper, inverse investigated case of single Hodgkin–Huxley neuron and small-world network, respectively. It found that can be modulated by excitation level, duration longer near threshold. Furthermore, we effect activity on collective discharge behavior network. We ...

Not all models are explanatory. Some models are data summaries. Some models sketch explanations but leave crucial details unspecified or hidden behind filler terms. Some models are used to conjecture a how-possibly explanation without regard to whether it is a how-actually explanation. I use the Hodgkin and Huxley model of the action potential to illustrate these ways thatmodels can be useful w...

Sodium entry during an action potential determines the energy efficiency of a neuron. The classic Hodgkin-Huxley model of action potential generation is notoriously inefficient in that regard with about 4 times more charges flowing through the membrane than the theoretical minimum required to achieve the observed depolarization. Yet, recent experimental results show that mammalian neurons are c...