History A three-year-old girl presented with a two-year history of recurrent , bi lateral ly distributed, asymptomatic papules mainly affecting the extensor surfaces of the upper and lower limbs. The lesions progressed to form pustules, crusts and were increasing in number. Some of these lesions healed with scarring and pigmentation. The girl was otherwise healthy with no systemic complaint or ...

Rarely attributed to Babinski is a phenomenon observed in patients with hemifacial spasm (HFS), which he first described in 1905. This “other Babinski sign”1 is manifested as follows: “when orbicularis oculi contracts and the eye closes, the internal part of the frontalis contracts at the same time, the eyebrow rises during eye occlusion,” “this set of occurrences is impossible to reproduce by ...

Aggressive fibromatosis is a rare tumor of borderline malignancy with a marked local aggressiveness. Surgery is the mainstay of treatment but complete tumor resection is often not easy to achieve without functional and cosmetic sequelae. We report a case of a pretreated child with aggressive fibromatosis who responded to hydroxyurea, avoiding the need for demolitive surgery.

PURPOSE to determine the prevalence of histopathological changes, in human placentas, related to hypertensive syndromes. METHODS a transversal study that compares histopathological changes identified in 43 placentae from hypertensive pregnant women (HypPr), with the ones from 33 placentae from normotensive pregnant women (NorPr). The weight, volume and macroscopic and microscopic occurrence o...

Coral reefs are biodiversity hotpots that are under significant threat due to the degradation and death of hard corals. When obligate coral-dwelling species die, the remaining species must either move or adjust to the altered conditions. Our goal was to investigate the effect of coral degradation on the ability of coral reef fishes to assess their risk of predation using alarm cues from injured...

It is now well established that subthalamic nucleus high-frequency stimulation (STN HFS) alleviates motor problems in Parkinson's disease. However, its efficacy for cognitive function remains a matter of debate. The aim of this study was to assess the effects of STN HFS in rats performing a visual attentional task. Bilateral STN HFS was applied in intact and in bilaterally dopamine (DA)-deplete...

The efficiency of neural circuits is modified by changes not only in synaptic strength, but also in intrinsic excitability of neurons. In CA1 hippocampal pyramidal neurons, bidirectional changes in the intrinsic excitability are often presented after induction of synaptic long-term potentiation or depression. This plasticity of intrinsic excitability has been identified as a cellular correlate ...

SYNOPSIS. Newly settled or hatched juveniles of marine benthic invertebrates generally experience very high mortality. Juvenile mortality can profoundly affect adult populations, but little is known about how individual variation in juvenile quality affects performance. Several recent studies have demonstrated that differences in size, larval nutrient stores, or larval feeding history can stron...

OBJECTIVE To test the hypothesis that occlusion-positive (OP) patients with blepharospasm (BEB) or hemifacial spasm (HFS) will benefit from a Bangerter occlusion foil (BOF), compared to occlusion-negative (ON) patients. OP/ON was based on immediate improvement in spasm with placement of a hand in front of either eye. DESIGN Prospective non-randomised single-centre pilot study. PARTICIPANTS ...

Electrical stimulation of the rodent medial prefrontal cortex (mPFC), including the infralimbic cortex (IL), immediately prior to or during fear extinction training facilitates extinction memory. Here we examined the effects of high-frequency stimulation (HFS) of the rat IL either prior to conditioning or following retrieval of the conditioned memory, on extinction of Pavlovian fear and conditi...