Water has anomalous properties that emanate from its hydrogen-bond-induced structure. Most of the unique properties ofwater are related to the network of strong three-dimensional hydrogen bonds that interconnect the water molecules [1, 2]. According to Stillinger [3], water has a preferential three-dimensional tetrahedral structure containing a few free or single-bonded water molecules. A simul...

Biological processes are the result of noncovalent, protein-ligand interactions, where the ligands range from small organic and inorganic molecules to lipids, nucleic acids, peptides, and proteins. Amide groups within proteins constantly exchange protons with water. When immersed in heavy water (D2O), mass spectrometry (MS) can measure the change of mass associated with the hydrogen to deuteriu...

Introduction. Orbital mapping of induced neutrons and gamma-rays by Odyssey has recently successfully proven the applicability of nuclear methods for studying of the elementary composition of Martian upper-most subsurface. In particular, the suite of Gamma-Ray Spectrometer (GRS) has discovered the presence of large water-ice rich regions southward and northward on Mars [1-3]. The data of neutro...

In order to erase reactive oxygen species (ROS) related with the proliferation of tumor cells by reducing activity of hydrogen, we developed functional water containing nano-bubbles (diameters: <900 nm for 71%/population) hydrogen of 1.1-1.5 ppm (the theoretical maximum: 1.6 ppm) with a reducing ability (an oxidation-reduction potential -650 mV, normal water: +100-200 mV) using a microporous-fi...

The energetics of water proximal to apolar groups is analyzed from a statistical perspective in the realistic context of polypeptide hydration. Analysis of a series of molecular dynamics simulations of a 16-residue polypeptide in water reveals a correlation between hydrogen bond energy and local packing when there is overcoordination of the water molecules around hydrogen bonds. We show that th...

Hydrogen has been reported to have neuron protective effects due to its antioxidant properties, but the effects of hydrogen on cognitive impairment due to senescence-related brain alterations and the underlying mechanisms have not been characterized. In this study, we investigated the efficacies of drinking hydrogen water for prevention of spatial memory decline and age-related brain alteration...

American Dental Association Health Foundation, Paffenbarger Research Center, National Institute of Standards and Technology, Gaithersburg, MD 20899-0001 Integrated near infrared (NIR) absorbance has been used to determine the absorptivity of the y2 + y3 combination band of the asymmetric stretch (y2) and the bending vibration (y3) for water in several organic solvents. Absorptivity measured in ...

The nearly linear relationship between hydrogen-bond strength at the CCSD(T)/Aug-cc-pVTZ level and the electron density at the bond critical point in the atoms-in-molecules theory provides a practical means of calculating the hydrogen-bond strength in liquid water. A statistical analysis of the hydrogen-bonds obtained from Car-Parrinello molecular dynamics simulations shows that the strengths o...

A combination of neutron diffraction augmented with isotopic substitution and computer modeling using empirical potential structure refinement has been used to extract detailed structural information for L-glutamic acid dissolved in 2 M NaOH solution. This work shows that the tetrahedral hydrogen bonding network in water is severely disrupted by the addition of glutamic acid and NaOH, with the ...

PURPOSE This study aimed to investigate the therapeutic potential of hydrogen-rich saline on pancreatic ischemia/reperfusion (I/R) injury in rats. METHODS Eighty heterotopic pancreas transplantations (HPT) were performed in syngenic rats. The receptors were randomized blindly into the following three groups: the HPT group and two groups that underwent transplantation and administration of hyd...