Kynurenines, the main products of tryptophan catabolism, possess both prooxidant and anioxidant effects. Having multiple neuroactive properties, kynurenines are implicated in the development of neurological and cognitive disorders, such as Alzheimer's, Parkinson's, and Huntington's diseases. Autoxidation of 3-hydroxykynurenine (3HOK) and its derivatives, 3-hydroxyanthranilic acid (3HAA) and xan...

Hematoporphyrin derivative, used in photodynamic therapy of cancer, was found to generate the cysteinyl free radical as seen by spin-trapping. Oxygen appears to be an absolute requirement for thiyl radical production. Singlet oxygen may be the initiating species since azide inhibits oxygen uptake and radical production. In addition, the hydroxyl radical, or a radical with similar reactivity, is...

Hydroxyl radical (·OH) can rapidly react with biological macromolecules, organic and inorganic substances on account of its strong oxidizing property, so it is widely used in sewage treatment, chemiluminescence analysis, macromolecule modification other fields. The strengthening effect Hydrodynamic cavitation chemical reactions depends the number free radicals initiated by cavitation. These are...

Antioxidants are widely considered as being essential for an optimal health so that supplementation with natural antioxidants is advised for cancer, cardiovascular diseases and other various pathologies, whereas supplementation with vitamin pills may not be advised, as discussed below. By clicking “antioxidant miracle” on a web search engine one gets about 2 million results. This mainly relates...