Please cite this article in press as: M.T. Kampm doi:10.1016/j.jphotobiol.2010.04.003 Multiple sclerosis (MS) risk is determined by environmental influences acting on the individual genetic background. Recent epidemiologic and experimental evidence supports a role of low environmental supplies of vitamin D in mediating an increased susceptibility to MS. We review available evidence suggesting t...

Background: Uncertainty exists about the impact of placental vit D metabolism on mother's blood levels in people. Objective: Awareness and how it affects amount metabolites was one goals this investigation. Methods: To take part a 14-week controlled feeding experiment, 27 third-trimester singleton pregnant women good health from Hayatabad Medical Complex during Jan 2022 to April 2022. Female tr...

The anticarcinogenic potential of vitamin D might be mediated by not only calcium metabolism but also other mechanisms initiated by vitamin D receptor (VDR). The authors measured plasma 25-hydroxyvitamin D in healthy volunteer examinees who underwent total colonoscopy in Tokyo, Japan, 2004-2005, and evaluated its influence on colorectal adenoma, both alone and in interaction with VDR polymorphi...

Vitamin D, discovered nearly a century ago, still receives intensive attention worldwide. In The Lancet today, Thomas Wang and colleagues, through a monumental eff ort by a large consortium of experts (the SUNLIGHT consortium), provide new data that help to explain the large variability of vitamin D status, as revealed by serum concentrations of 25-hydroxyvitamin D. Vitamin D defi ciency, even ...

BACKGROUND Vitamin D is important to health and disease. Liquid chromatography-tandem mass spectrometry (LC-MSMS) is considered the most accurate technology for quantification of serum 25-hydroxyvitamin D (25OHD) which is the best biomarker for estimating vitamin D nutritional status. METHODS Serum was mixed with acetonitrile containing hexadeuterated 25-hydroxyvitamin D(3) (d(6)-25OHD3) and ...

The prevalence of metabolic disease in a population of 68 postgastrectomy patients was assessed using histomorphometric evaluation of transiliac bone biopsy specimens after tetracycline double labelling. Trabecular bone volume was significantly lower in the postgastrectomy group (p less than 0.01): 62% of the patients had increased osteoid surface, 56% increased osteoid thickness, and 24% incre...

Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease that disproportionately affects African American females. The causes of SLE are unknown but postulated to be a combination of genetic predisposition and environmental triggers. Vitamin D deficiency is one of the possible environmental triggers. In this study we evaluated relationships between vitamin D status, cellular ...

Abstract Evaluation of digital ELISA using a high-resolution computational optical system for measurement total 25-hydroxyvitamin D Background Biomarkers such as vitamin occur at very low concentrations in blood, and sensitive detection methods are required order to measure them. It is difficult accurately low-concentration biomarkers conventional enzyme-linked immunosorbent assays (ELISA) with...