This study was aimed to determine the effects of different concentrations L-phenylalanine (0.25, 0.50 and 1.00 mM L-Phe) applied adventitious root cultures for culture durations on growth production tropane alkaloids phenolics in Hyoscyamus niger. For this purpose, roots obtained from petiole explants vitro seedlings were used as plant materials. After cultured liquid Murashige Skoog (MS) mediu...

Black henbane (BH) or Hyoscyamus niger, has been used as a medicine since last centuries and has been described in all traditional medicines. It applies as a herbal medicine, but may induce intoxication accidentally or intentionally. All part of BH including leaves, seeds and roots contain some alkaloids such as Hyoscyamine, Atropine, Tropane and Scopolamine. BH has pharmacological effects like...

background: plants infection with microorganisms as well as physical factors such as osmotic stresses especially drought stress induced particular secondary metabolite production. objective: plant root and shoot hyoscyamine (hyo) and scopolamine (sco) variations were investigated under three water deficit stress (wds) levels as 30 (w1), 60 (w2) and 90 % (w3) water depletion of field capacity an...

OBJECTIVE To investigate the neuropsychopharmacological effect of a polyherbal formulation (PHF) on the learning and memory processes in rats. MATERIALS AND METHODS PHF contains Withania somnifera (Ashwagandha), Nardostachys jatamansi (Jatamansi), Rauwolfia serpentina (Sarpagandha), Evolvulus alsinoides (Shankhpushpi), Asparagus racemosus (Shatavari), Emblica officinalis (Amalki), Mucuna prur...

Tropane alkaloids, especially hyoscyamine (HYO) and scopolamine (SCO), are widely used in medicine for their antispasmodic, anticholinergic, and sedative properties. This study was undertaken to investigate the root and shoot tropane alkaloids production from in vitro shoot tip (as explant) culture of Hyoscyamus niger under different plant growth regulators including auxins (IAA, 2, 4-D, IBA, N...