668 defined, hemispherical, nontender, noncompressible, boggy swelling, abutting the lower margin of the plaque. A few satellite, hyperpigmented papules were present over the thighs in the periphery of the main lesion. The patient denied any history of bleeding or ulceration of the plaque. There was no evidence of sweating or excessive growth of lanugo hair over the plaque. Thrill and bruit wer...

An acrochordon is a small, soft, common, benign, usually pedunculated neoplasm that is found particularly in persons who are obese. It is usually skin colored or hyperpigmented, and it may appear as surface nodules or papillomas on healthy skin. Most acrochordons vary in size from 2-5 mm in diameter, although larger acrochordons up to 5 cm in diameter are sometimes evident. The most frequent lo...

A 26-year-old woman was regularly followed up in a gastro-intestinal out-patient clinic. Since early childhood, she was noted to have hyperpigmented lesions over the perioral region (Fig 1a) and fingers (Fig 1b), and a history of small intestinal intussusception due to polyps that was treated by surgery when she was 12 years old. Endoscopic assessment revealed multiple gastric polyps (Fig 1c) a...

Received June 2008 Accepted September 2008 INTRODUCTION Neurofibromatosis is an autosomal dominant progressive disorder with an incidence of approximately 1 in 3000 live births.(1) Its recognized features include hyperpigmented skin lesions (cafe-au-lait spots), neurofibromas, iris hamartomas, macrocephaly, central nervous system tumors, defects of the skull and facial bones, and vascular lesio...

Previous reports have shown the association between familial spastic paraplegia and hypopigmentation of the skin. A family is reported in which three siblings presented with progressive spastic paraparesis and cerebellar ataxia. All the siblings had large hyperpigmented naevi of the lower extremities while none of the unaffected members had a skin lesion. A definite association appears to exist...

Erythema dyschromicum perstans (EDP) and Lichen planus pigmentosus (LPP) are both inflammatory disorders of pigmentation with unknown etiology difficult to differentiate clinically histologicaly. There is no consensus on whether entities separate or belong the same spectrum cutaneous disorders. We present a 13 year old boy mostly asymptomatic hyperpigmented lesions over body. The were subsequen...

the dynamic response of a transversely isotropic, linearly elastic layer bonded to the surface of a half-space of a different transversely isotropic material under arbitrary shape surface loads is considered. with the help of displacements and stresses green’s functions, an analytical formulation is presented for the determination of the displacements and stresses at any point in both surface l...

Physical examination A reticulate hyperpigmented macular rash was present at the axillae, groins, extensor aspect of the upper limbs, buttocks, and thighs (Figure 1). Poikilodermatous changes were observed, with hypopigmented macules, epidermal atrophy and telangiectasia (Figure 2). Erythematous patches with epidermal atrophy were also seen, especially over the abdomen and chest (Figure 3). The...

A 6 year-old male patient was admitted to the dermatology department with an eruption on the right arm, chest and left leg. No clinical symptoms such as pain, pruritus or previous inflammation were present. His mother reported that the lesion had developed four years ago as small-sized hyperpigmented macules which enlarged in a short period of time as band-like hyperpigmentation, and then remai...

Pityriasis versicolor is a superficial fungal infection of the skin caused by yeast of the genus Malassezia. It is characterized by hypopigmented or hyperpigmented macules and patches usually involving the trunk [1]. The variants of pityriasis versicolor include hypochromic, hyperchromic, combination of hypo-hyperchromic, erythematous, circinate, atrophic and acral [2-4]. However, the follicula...