BACKGROUND Several case series and reports describe paraphilia as occurring after brain damage, mostly in the frontal lobes and diencephalic structures. Hypersexuality and paraphilic behaviors are also documented in a variety of other neurologic disorders, (e.g., Kluver Bucy syndrome, and more rarely in multiple sclerosis). In multiple sclerosis, hypersexual behavior and paraphilias have been a...

We present the case of a 71-year-old right-handed male, admitted to the Department of Neurology, Emergency County Hospital of Arad, Romania, on November 2015, with a rare case of Klüver-Bucy syndrome (KBS), following an ischemic stroke of the right temporal lobe, which was previously diagnosed in December 2014 and was treated accordingly. At the moment of second hospital admission, the patient ...

Background and aims There are significant gaps in knowledge regarding the role of childhood adversity, interpersonal violence, and suicidal behavior in hypersexual disorder (HD). The aim of this study was to investigate interpersonal violence in hypersexual men compared with healthy volunteers and the experience of violence in relation to suicidal behavior. Methods This case-control study inclu...

Kafka (2009) has done an exemplary job of synthesizing disparate perspectives on dysregulated sexuality, and distilling the common elements into Hypersexual Disorder, a proposed new diagnosis for the fifth edition of the Diagnostic and Statistical ManualofMentalDisorders.Thereappears tobesubstantialclinical support for this disorder; however, strong empirical evidence demonstrating its validity...

Abstract Introduction Sexual emergencies in female patients are more common than people think. They represent medical curiosities pathologies for which we should be prepared to treat. This review and the presentation of our cases shows how extensive important is this area practice why every single physician confront them. Gynecologist, surgeons, sexologists, ER physicians familiarized with some...

Apathy and impulsivity are two major comorbid syndromes of Parkinson's disease (PD) that may represent two extremes of a behavioral spectrum modulated by dopamine-dependent processes. PD is characterized by a progressive loss of dopaminergic neurons in the substantia nigra pars compacta to which are attributed the cardinal motor symptoms of the disorder. Dopamine replacement therapy (DRT), used...

Impulsive-compulsive behaviours are a significant source of morbidity for patients with Parkinson's disease receiving dopaminergic therapy. The development of these behaviours may reflect sensitization of the neural response to non-drug rewards, similar to that proposed for sensitization to drug rewards in addiction. Here, by using (11)C-raclopride positron emission tomography imaging, we inves...

To the Editor: We read with great interest the recent article by Korpelainen et al.1 Despite the fact that the majority of their patients reported a marked decline in all the measured sexual functioning, there was increased libido in 19 of their 192 patients. These patients did not differ from other patients as to the site of the lesion, as reported before.2–4 However, no information was presen...