From July 1998 to November 1999 we have followed up 15712 deliveries (12044 vaginal and 3668 cesarean section) in our hospital. Among these, 182 cases were primarily diagnosed as intrauterine growth restriction (IUGR) and 248 pregnancies were complicated with hypertensive disorders. In these two groups we have investigated the outcome of the neonates. Neonatal weight under the 10th percent...

We studied 74 never-treated grade I hypertensive subjects aged 18 to 45 years and 20 normotensive control subjects to define the rate of increase in carotid intima-media thickness (IMT) and the potential role played by the various risk factors. IMT was assessed as mean IMT and as maximum IMT in the right and left common carotid artery, carotid bulb, and internal carotid artery at baseline and a...

BACKGROUND Systemic hypertension (HTN) and obstructive sleep apnea (OSA) are individually associated with left ventricular structural and functional adaptations. However, little is known about the impact of OSA on the left ventricle in Africans with HTN. AIM The aim of this study is to determine the association between OSA and left ventricular mass (LVM) and diastolic dysfunction in Nigerian ...

OBJECTIVE To evaluate trends and associations of hypertensive disorders of pregnancy with stroke risk and test the hypothesis that hypertensive disorders of pregnancy-associated stroke results in higher rates of stroke-related complications than pregnancy-associated stroke without hypertensive disorders. METHODS A cross-sectional study was performed using 81,983,216 pregnancy hospitalizations...

Aims To compare the prognostic implication of stress echocardiography (SE) in a large cohort of hypertensive and normotensive patients with known or suspected coronary artery disease (CAD). The relative prognostic meaning of the SE result in hypertensive and normotensive patients remains to be addressed. Methods and results The study group was formed by 11 542 patients (6214 hypertensive patien...

The aims of this study were to determine the relations between platelet free calcium concentrations ([CaD, intracellular pH (pH,), and aggregation and to assess the effects of angiotensin II (Ang II) and endothelin-1 on these platelet parameters in normotensive subjects and hypertensive patients. Seventeen normotensive subjects, 25 untreated hypertensive patients, and 34 treated hypertensive pa...

Hypertensive crisis is a serious condition that is associated with end-organ damage or may result in end-organ damage if left untreated. Causes of acute rises in blood pressure include medications,noncompliance, and poorly controlled chronic hypertension. Treatment of a hypertensive crisis should be tailored to each individual based on the extent of end-organ injury and comorbid conditions. Pro...

To evaluate the impact of various regimens antihypertensive treatment on blood pressure and target organs in nonadherent hypertensive patients.

The relationship of lysosomes to the vascular effects of hypertension and the possible modification of these effects by anti-inflammatory agents (methylprednisolone and aspirin), vitamin E, and estrogen were studied. Each of these agents was given to a group of hypertensive rats; untreated hypertensive rats and normotensive rats served as controls. Vessel wall morphology and dimensions of aorta...