BACKGROUND Prophylactic and preemptive strategies are used to prevent cytomegalovirus (CMV) infections after solid organ transplant. We assessed the safety and efficacy of both strategies for CMV prevention. METHODS A DerSimonian and Laird random-effects model was used for pooling the data, and Q statistic and I(2) methods were used to assess statistical heterogeneity. RESULTS Twenty studie...

background: thalassemia syndromes are the most common genetic disorders in the world. they happen due to genetic defects in process of haemoglobin synthesis, and would be classified to many groups mainly α and β, based on the kind of defect. anemia is the main clinical manifestation of this phenotype of disorder. in order to correct the chronic anemia in thalassaemic individuals, they may need ...

As the Director General of Keio University Hospital, I hereby document recent outbreak health care-associated novel coronavirus (SARS-CoV-2) COVID-19 infections at our hospital in spring 2020.

Zymoseptoria tritici is the causal fungus of Septoria blotch (STB), a globally important foliar disease wheat. Infections by more than one strain pathogen, or co-infections, are known to be most prevalent form infection in field. The impact that co-infection Z. has on severity for plant host and its effect defence not fully understood. Here, isolates were extracted from STB-presenting leaves UK...

Although type I interferons (IFN-I) were initially defined as potent antiviral agents, they can also cause decreased host resistance to some bacterial and viral infections. The many antiviral functions of the IFN-I include direct suppression of viral replication and activation of the immune response against viruses. In addition to their antiviral effects, IFN-I are also protective against sever...

background: fusarium species are capable of causing a wide range of crop plants infections as well as uncommon hu­man infections. many species of the genus produce mycotoxins, which are responsible for acute or chronic diseases in ani­mals and humans. identification of fusaria to the species level is necessary for biological, epidemiological, pathologi­cal, and toxicological purposes. in this s...

Type I interferons (IFNs) were first described for their ability to protect the host from viral infections and may also have beneficial effects under specific conditions within some bacterial infections. Yet, these pleiotropic cytokines are now known to exacerbate infections by numerous life-threatening bacteria, including the intracellular pathogens Listeria monocytogenes and Mycobacterium tub...

I NFECTIONS with the herpes group of viruses are the most common viral infections following pediatric liver transplantation. I Adenoviral infections, though uncommon, are being increasingly recognized following organ transplantation.2.~ We have previously reported our initial experience with adenoviral infections in children receiving liver transplants. 6 Subsequently. our experience has furthe...

AbstractObjectives Chronic infections by enteric parasites including protist and helminthic species produce long-term sequelae on the health status of infected children. This study assesses potential associations linked with parasite in symptomatic asymptomatic children Zambézia province, Mozambique. Methods In this prospective cross-sectional study, stool samples epi...