cladribine, an analogue of deoxyadenosine, is highly toxic for both non-dividing and proliferating cells and has shown activity in the treatment of several malignancies. therefore, the aim of the present study is to investigate the cytotoxicity effect of cladribine (2-cda) on the breast cancer cell line, mcf-7 (estrogen receptor positive, er+). mtt assay, annexin v-fluorescein/pi and hoechst 33...

The variation of the energy spectrum of n±i±p±i crystals under excitation was examined and the influence of the reduction of the screening length on the ratio between the coefficient of diffusion and the mobility of the current carriers was established. It is shown that the filling of subband states by carriers results in an anomalous behaviour of the diffusivity±mobility ratio. The effect occu...

soybean isoflavone genistein has multiple anticancer properties and its pro-apoptotic and anti-proliferative effects have been studied in different cancer cells. however, the mechanisms of action of genistein and its molecular targets on human colon cells have not been fully elucidated. therefore, caspase-3 and p38 mitogen-activated protein kinase (p38 mapk) as the main therapeutic targets were...

In this article. the results of an initial attempt to estimate the effects of state attributes on plant location and investment expenditure were presented for the forest products industry in the southern United States. A conditionallogit model was used to analyze new plant births, and a timeseries cross-section model to assess the total capital expenditure. Significant positive effects were fou...

The band structure of compensated n-i-p-i doping superlattices has been investigated for the first time by using the multistep-potential approach as the real potential form and by using numerical calculations. The dispersion of compensated n-i-p-i superlattices is shown to be stronger than that of compositional superlattices. The Srst three allowed conduction minibands and forbidden rninigaps a...