BACKGROUND Irritable bowel syndrome (IBS) and functional dyspepsia (FD) show considerable overlap and are both associated with psychiatric comorbidity. The present study aimed to investigate whether IBS patients with FD show higher levels of psychopathology than those without FD. As a preliminary analysis, it also evaluated the psychopathological differences, if any, between IBS patients featur...

BACKGROUND Diarrhea-predominant irritable bowel syndrome (IBS-D) impairs patient quality of life (QOL). Rifaximin is an oral, nonsystemic antibiotic indicated for IBS-D. The objective of this secondary analysis was to evaluate rifaximin retreatment on IBS-related QOL in patients with IBS-D. METHODS Patients received open-label rifaximin 550 mg three times daily for 2 weeks. Clinical responder...

Introduction: Polycystic ovary syndrome (PCOS) causes endocrine disorders that affect the functioning of reproductive system and body's metabolic system. Bowel movement abdominal pain are common complaints PCOS patients. Few studies have been performed on relationship between irritable bowel (IBS), association two syndromes is unclear.
 Material Method: In study, 72 patients were enrolled ...

Currently, the Malaysian construction industry is focusing on transforming construction processes from conventional building methods to the Industrialized Building System (IBS). Still, research on the decision making of IBS technology adoption with the influence of contextual factors is scarce. The purpose of this paper is to explore how contextual factors influence the IBS decision making in b...

BACKGROUND Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders with chronic abdominal pain and altered bowel habit without any organic reason. Sleep disorders may be associated to IBS. OBJECTIVE We aimed to assess sleep disturbances and depression-anxiety-stress in IBS patients. METHODS In this analytical cross sectional study from November 2013 to...

Biological markers that measure gut health and diagnose functional gastro-intestinal (GI) disorders, such as irritable bowel syndrome (IBS), are lacking. The objective was to identify and validate a biomarker panel associated with the pathophysiology of IBS that discriminates IBS from healthy controls (HC), and correlates with GI symptom severity. In a case-control design, various plasma and fe...

Irritable Bowel Syndrome (IBS) is multifactorial in its etiology and heterogeneous in its clinical presentation and pathogenesis. It is recognized that inflammation plays an important role in symptom generation, at least in a subset of patients with IBS. Previous gastroenteritis has been identified as the most important risk factor for IBS, and several studies reported that a substantial propor...

Irritable bowel syndrome (IBS) is a poorly understood disorder characterized by persistent symptoms, including visceral pain. Studies have demonstrated oral microbiome differences in inflammatory bowel diseases suggesting the potential of the oral microbiome in the study of non-oral conditions. In this exploratory study we examine whether differences exist in the oral microbiome of IBS particip...

BACKGROUND The diagnosis of irritable bowel syndrome (IBS) is based on clinical criteria. Further diagnostic testing is advised for certain "red flag" alarm or warning signs. AIM This investigation was designed to examine the yield of testing for "red flags". METHODS Consecutive patients who were prospectively evaluated and met the ROME III criteria for IBS were reviewed for "red flags" whi...

inflammatory component of IBS. A proportion of patients with diarrhea-predominant IBS recall acute infectious enteritis as a boot for the onset of their symptoms, and 7%-33% of patients with acute bacterial enteritis will experience IBS symptoms for over 6 months. A chronic latent inflammation has been documented in mucosal biopsies of these patients. Post-infectious IBS (PI-IBS) has been linke...