Manufacturing Engineering Centre, Cardiff University, Queen’s Building, The Parade, Newport Road, Cardiff CF24 3AA, Wales, UK Minerals & Materials Processing Division, Korea Institute of Geoscience & Mineral Resources, 92 Gwahangno, Yuseong-gu, Daejeon 305-350, Korea Ultrapure Materials Division, Centre for Materials for Electronics Technology (C-MET), IDA, Phase-III, Cherlapally, HCL-Post, Hyd...

The authors introduce an ontology for the study of how animals think, as well as a comprehensive model of human and animal cognition utilizing the ontology. The IDA (Intelligent Distribution Agent) model of cognition, a computational and conceptual model derived from a working software agent, is described within the framework of the ontology. The model is built on functional needs of animals, r...

This paper develops a modest proposal for introducing final outcome indicators in the IDA aid allocation formula. It starts with a review of the current formula and the rationale for it. It is argued that this formula, and in particular the Country Policy and Institutional Assessment (CPIA) part of it, implicitly relies too heavily on a uniform model of what works in development policy. Even if...

Miliaria is a disorder of the eccrine sweat glands which occurs in conditions of increased heat and humidity. It can be associated with persistent febrile states as well as with certain drugs. We presented a 40 year-old female with myelodysplastic syndrome and progression to acute myelogenous leukemia who was admitted to the hospital for chemotherapy induction. The patient was treated with idar...

We analyzed the outcome of a series of 19 newly diagnosed patients with acute promyelocytic leukemia treated with AIDA modified protocol, using mitoxantrone in place of idarubicin. Eleven patients achieved morphologic CR (58%). The remaining 8 patients had induction failure due to death during induction. Ten of eleven patients in CR achieved molecular remission after induction therapy and all t...

J.m., a 43-year-old man with acute myelogenous leukemia with a monosomy 7 cytogenetic abnormality, received an allogeneic hematopoietic stem cell transplantation (HscT) from his human leukocyte antigen– matched brother. Past treatments included idarubicin and cytarabine induction therapy followed by a cycle of high-dose cytarabine. J.m. was in complete remission prior to the HscT. The condition...

A 39-year-old woman was diagnosed as having immune thrombocytopenia (ITP) in 1981 in another hospital, and she was well controlled with prednisolone. No other immunosuppressive drugs, such as cyclosporine or azathioprine, were used. In 1997, she was diagnosed as having acute megakaryoblastic leukemia (AML-M7) in another hospital. Blasts showed the absence of peroxidase (POX) and positive platel...

A 50-year-old non-diabetic woman was admitted for hemorrhagic diathesis. Laboratory examination indicated that she was suffering from t(15;17)-positive acute promyelocytic leukemia associated with disseminated intravascular coagulation. She was started on all-trans retinoic acid plus idarubicin and cytarabine. However, due to the development of retinoic acid syndrome, all-trans retinoic acid wa...

Shwachman-Diamond syndrome (SDS) is a rare genetic disorder of unknown pathogenesis involving exocrine pancreatic insufficiency and hematological and skeletal abnormalities. About 25% of patients develop hematopoietic malignancies. We report on a case of acute myeloid leukemia (M2) in a 21-year-old woman affected by SDS. She was treated with conventional chemotherapy (idarubicin plus cytarabine...

Acute promyelocytic leukemia with concurrent myeloid sarcoma is a rare clinical event. Herein we describe a patient that presented with back pain and bilateral leg weakness caused by spinal cord compression due to extramedullary deposition of leukemic cells. Acute promyelocytic leukemia was suspected based on immunophenotypic findings of malignant cells in bone marrow aspirate. The diagnosis wa...