Objective To assess visual and anatomical outcome of full thickness macular hole (FTMH) surgery with ILM peeling using brilliant blue G dye. Methods Thirty patients who had clinically evident macular hole were selected. Pre-operative Optical Coherence Tomography (OCT) was done. In all cases vitrectomy was performed via 23guage 3 ports pars plana (3PPV) vitrectomy system and Brilliant blue G d...

Purpose. To investigate the surgical outcomes of Viscoat® assisted inverted internal limiting membrane (ILM) flap technique for large macular holes (MHs) associated with high myopia. Design. Prospective, interventional case series. Methods. Fifteen eyes of 15 patients with high myopia underwent vitrectomy and Viscoat assisted inverted ILM flap technique to treat MH without RD. Patients were fol...

PURPOSE Intraocular stem cell transplantation may be therapeutic for retinal neurodegenerative diseases such as glaucoma via neuronal replacement and/or neuroprotection. However, efficacy is hindered by extremely poor retinal graft integration. The purpose was to identify the major barrier to retinal integration of intravitreally transplanted stem cells, which was hypothesized to include the ce...

PURPOSE Concern has been raised about the retinal toxicity of vital dyes. We designed a prospective study to determine the possible toxicity of trypan-blue (TB) in macular hole surgery with TB-assisted internal limiting membrane (ILM) peeling through the performance of electroretinograms (ERGs). METHODS Patients diagnosed with a macular hole underwent ophthalmological evaluation prior to surg...

PURPOSE To report the use of intraoperative spectral domain optical coherence tomography (SD-OCT) for detecting anatomical changes during macular surgery. METHODS In a consecutive case series, 32 eyes of 32 patients undergoing concurrent pars plana vitrectomy and intraoperative SD-OCT for macular hole (MH), epiretinal membrane (ERM) and vitreomacular traction (VMT) were enrolled. Intraoperati...

PURPOSE Internal limiting membrane (ILM) peeling in macular hole surgery may allow a shortened period of face down positioning. This study reports the results of macular hole surgery combined with shortened (3-day) face down positioning. METHODS The study was a retrospective review of data for 21 patients (21 eyes) treated for a macular hole by a single surgeon (G.K.S.). All patients underwen...

PURPOSE To improve understanding of vision loss and clinical findings, we studied gross and microscopic pathology of retinas and optic nerves of individuals with Terson's syndrome. DESIGN Retrospective case series with clinicopathologic correlation. PARTICIPANTS We included 109 deceased individuals with Terson's syndrome. METHODS Histologic sections and gross photographs from 109 cases of...

This paper aims at setting the context for privacy-aware information lifecycle management within enterprises, i.e. the process of handling the lifecycle of personal and confidential information in a way that is compliant with privacy laws and people’s expectations (including data retention, deletion, notifications, data transformation, etc.). Despite the fact that enterprises are already using ...

PURPOSE To evaluate the potential of brilliant blue G (BBG) and indocyanine green (ICG) for intraoperative staining of the internal limiting membrane (ILM) with respect to perceivable contrast. METHODS In a retrospective clinical case series the authors analyzed 26 consecutive chromovitrectomy interventions in 26 patients with macular holes, epiretinal fibrosis, vitreoretinal traction syndrom...

PURPOSE To describe the appearance of inner retinal defects using en face spectral domain optical coherence tomography (SD-OCT) after idiopathic full-thickness macular hole (FTMH) surgery, referred to as concentric macular dark spots (CMDS). METHODS In a retrospective cohort study, the authors evaluated 36 eyes of 36 patients with large idiopathic MH (>400 μm) who underwent standard three-por...