Aim: The present study was intended to develop some novel imidazole derivatives via multi-component reaction catalysed by Ceric Ammonium Nitrate (CAN) in polyethylene glycol-400 (PEG-400) and its HMG-CoA reductase inhibitory activity for benefit in atherosclerosis. Methods: The one-pot synthesis has been achieved by taking benzyl, benzaldehyde, 3-amino-1, 2, 4triazole-5carboxylic acid (0.01 mol...