نتایج جستجو برای: immunodominant protein

تعداد نتایج: 1236524  

2016
Hui-Jie Yang Jin-Yong Zhang Chao Wei Liu-Yang Yang Qian-Fei Zuo Yuan Zhuang You-Jun Feng Swaminath Srinivas Hao Zeng Quan-Ming Zou Paulo Lee Ho

Vaccination strategies for Staphylococcus aureus, particularly methicillin-resistant S. aureus (MRSA) infections have attracted much research attention. Recent efforts have been made to select manganese transport protein C, or manganese binding surface lipoprotein C (MntC), which is a metal ion associated with pathogen nutrition uptake, as potential candidates for an S. aureus vaccine. Although...

Journal: :Journal of immunology 2000
N Blake T Haigh G Shaka'a D Croom-Carter A Rickinson

Mouse models suggest that the processing of exogenous Ag by dendritic cells can be important for priming the CD8(+) CTL response. To study the situation in humans, we have exploited the CTL response to EBV infection. In this context EBV expresses eight latent proteins, of which EBV-encoded nuclear Ag (EBNA) 3A, 3B, and 3C appear to be immunodominant for CTL responses, whereas another nuclear Ag...

2016
Hui Dong Xin Zhang Hongyan Shi Jianfei Chen Da Shi Yunnuan Zhu Li Feng

The coronavirus membrane (M) protein acts as a dominant immunogen and is a major player in virus assembly. In this study, we prepared two monoclonal antibodies (mAbs; 1C3 and 4C7) directed against the transmissible gastroenteritis virus (TGEV) M protein. The 1C3 and 4C7 mAbs both reacted with the native TGEV M protein in western blotting and immunofluorescence (IFA) assays. Two linear epitopes,...

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