نتایج جستجو برای: immunoglobulin gene
تعداد نتایج: 1191465 فیلتر نتایج به سال:
abstract kawasaki disease is a systemic vasculitis that mainly affects younger children. although the definite cause still remains unknown but the clinical and epidemiologic findings discuss an infectious cause. the prevalence of incomplete kawasaki disease reported 15 to 36.2%, and it is more frequent in the extremes of the age spectrum. non delayed treatment of disease should be initiated bec...
Background: The results indicated that the immunologic and genetic factors play a key role in the susceptibility to this syndrome compared to other risk factors. Immunoglobulin G, representing approximately 80% of Immunoglobulins in humans and the only way that IgG2 can be passed from mother to fetus blood circulation is binding to Fcgamma receptor (FcγR) classes which have been coded by Fcgamm...
It is generally accepted that in the maturation of an immune response, the quality of the antibody, as well as the quantity, will improve with time after immunization. In the mouse system, immunoglobulin obtained in the first days after immunization with NP-CGG showed greater specificity to NIP-CGG (heteroclitic specificity). While the specificity to the immunizing antigen (homoclitic specifici...
The human peripheral B-cell compartment displays a large population of immunoglobulin M-positive, immunoglobulin D-positive CD27(+) (IgM(+)IgD(+)CD27(+)) "memory" B cells carrying a mutated immunoglobulin receptor. By means of phenotypic analysis, complementarity-determining region 3 (CDR3) spectratyping during a T-independent response, and gene-expression profiling of the different blood and s...
Abstract Netherton syndrome is a rare genetic disorder inherited in an autosomal recessive pattern. Mutations the serine protease inhibitor Kazal-type 5 ( SPINK5 ) gene are responsible for this disorder. can have multisystemic effects primarily involving hair, skin and immune system. Currently, no definitive treatment has been reported beyond supportive care. Herein, we report case of newborn d...
BACKGROUND Regular intravenous immunoglobulin treatment is used to replace antibody deficiency in primary immunodeficiency diseases; however the therapeutic effect seems to be related not only to antibody replacement but also to an active role in the modulation of the immune response. Common variable immunodeficiency is the most frequent primary immunodeficiency seen in clinical practice. MET...
Background: Children with idiopathic thrombocytopenic purpura who are treated with intravenous immunoglobulin therapy might experience a decline in their absolute neutrophil count. The aim of this study was to investigate the incidence of neutropenia following intravenous immunoglobulin therapy in children with idiopathic thrombocytopenic purpura undergoing intravenous immunoglobulin therapy. ...
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