Chimeric antigen receptor T (CAR-T) cell therapy has led to a paradigm change in cancer treatment. To allow widespread use of this therapy, it is important reduce the costs associated with cells manufacturing whilst ensuring high-quality production. Online biosensors can help monitor real time effectiveness engineering CAR-T cells, possibility be integrated on workflow without need extract samp...

We report here an impedimetric genosensor for the quantification of microRNA-21 using [Fe(CN)6]3?/4? as redox probe to transduce hybridization event. The biosensing platform was built at a thiolated-gold electrode by covalent bond reduced graphene oxide (RGO) modified with chitosan (CHIT) and further attachment aminated DNA probe. GO used provide carboxylic groups CHIT and, once reduced, improv...

COVID-19, a viral respiratory illness, is caused by Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2), which was first identified in Wuhan, China, 2019 and rapidly spread worldwide. Testing isolation were essential to control the virus’s transmission due severity of disease. In this context, there global interest feasibility employing nano-biosensors, especially those using graphene...