T he function of the p53 tumor suppressor protein is finely tuned through a myriad of interactions with other proteins. These interactions can lead to posttranslational modifications that regulate p53 stability, DNA binding, or promoterspecific transcriptional activation. A number of p53 binding proteins serve as cofactors that participate in the recruitment of p53 to specific promoters and fac...

Fault diagnosis of monoblock centrifugal pump essentially forms a pattern recognition problem. There are three important steps to be performed in pattern recognition namely feature extraction, feature selection and classification. In this study, stationary wavelet transform (SWT) is used for feature extraction and SMO algorithm (a WEKA implementation of Support Vector Machine (SVM) algorithm) i...

In robust nonparametric kernel regression context,weprescribemethod to select trimming parameter and bandwidth. Through solving estimating equations, we control outlier effect through combining weighting and trimming. We show asymptotic consistency, establish bias, variance properties and derive asymptotics. © 2016 Elsevier B.V. All rights reserved.

In this work an innovative system for wind power generation in urban areas is proposed. The generation system substitutes the roof of the building and it consists of a static part, the stator, and a moving part, called impeller or rotor, which is a centripetal turbine with vertical axis of rotation. The rotary motion of the rotor is transferred through a shaft to a generator that produces elect...

The purposes of inlet and outlet devices for rotary blood pumps, including inducers and diffusers for axial pumps, inlet and exit volutes for centrifugal pumps, and inlet and outlet cannulas, are to guide the blood into the impeller, where the blood is accelerated, and to convert the high kinetic energy into pressure after the impeller discharge, respectively. The designs of the inlet and outle...

The purpose of this study is to investigate a small centrifugal cooling fan applied on notebook computers, which is consisted of a forward-curved impeller and a centrifugal housing. First of all, a basic rotor impeller is designed with the cascade theory. To manufacture the mock-up for experimental verification, the design fan will be expressed in the CAD/CAM format for the CNC machine. All exp...