BACKGROUND AND PURPOSE A preoperative prediction of the 360 degrees point insertion depth would aid the planning of electric acoustic stimulation (EAS) implantation. The purpose of this study was to establish whether the distance between the round window and the opposite cochlear wall on CT or MR imaging may be used to predict the length of a cochlear implant electrode array required to be inse...

OBJECTIVE To reassess endometrial morphological criteria of normality identifying the best morphological and molecular "implantation window" indicators in normal women. DESIGN Prospective clinical study. SETTING Assisted reproductive unit. PATIENT(S) Fourteen healthy volunteers. INTERVENTION(S) Blood sampling for LH, E(2), and progesterone (P4) determinations. Daily vaginal ultrasounds....

Both the increasing usage of intratympanic medication to the inner ear through the round window and the popularity of cochlear implantation have raised interest in the anatomy of the round-window niche (RWN). The objectives of this study were to measure the RWN and to standardize a computed tomographic projection for measuring it. We included patients of all ages who underwent computed tomograp...

This review gives an overview of the mechanisms of action of oral emergency contraception pills (ECPs), focusing on the levonorgestrel (LNG) and ulipristal acetate (UPA) containing ECPs. In vivo and in vitro studies have addressed the effect of EC on various possible targets. Based on these studies as well as on clinical trials it is clear that the efficacy of ECPs to prevent an unintended preg...

BACKGROUND Computed tomography (CT)-guided percutaneous implantation of 125 Iodine radioactive seeds requires the precise arrangement of seeds by tumor shape. We tested whether selecting target areas, including subclinical areas around tumors, can influence locoregional recurrence in patients with non-small cell lung cancer (NSCLC). METHOD We divided 82 patients with NSCLC into two groups. Ta...

We present, for the first time an in vivo implementation of dynamic light scattering (DLS) adapted to optical coherence tomography (OCT). Human bladder carcinoma tumors were grown in dorsal skin-fold window chambers fitted to male nude mice and imaged at a rate of 200 Hz using OCT. Maps of speckle decorrelation times (DT) were generated for regions of skin from individual mice as well as for re...

Piston-stapedotomy is the most common method for hearing restoration in patients with otosclerosis. In this study, we have experimentally examined a prototype of a new chamber stapes prosthesis. The prototype was implanted in a human cadaver temporal bone. The round window vibrations before and after implantation were measured for the acoustic signal (90 dB SPL, 0.8-8 kHz) in the external audit...

During embryo implantation, the blastocyst interacts with and regulates the endometrium, and endometrial fluid secreted by the endometrial epithelium nurtures the embryo. Here, we propose that maternal microRNAs (miRNAs) might act as transcriptomic modifier of the pre-implantation embryo. Microarray profiling revealed that six of 27 specific, maternal miRNAs were differentially expressed in the...

PURPOSE Neuromodulation of sacral roots is an alternative mode of therapy for patients with urge incontinence or detrusor hypocontractility. We investigated the effects of sacral (S3) nerve stimulation in patients using a new surgical approach for sacral neuromodulator implantation. Modification of the implantation method with sacral laminectomy and bilateral electrode placement led to distinct...

Implantation of an embryo occurs during the mid-secretory phase of the menstrual cycle, known as the "implantation window." During this implantation period, there are significant morphologic and functional changes in the endometrium, which is followed by decidualization. Many immune cells, such as dendritic and natural killer (NK) cells, increase in number in this period and early pregnancy. Re...